Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP

10.3389/fnbeh.2015.00299

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Main Authors: Nizetic, D, Chen, C.L, Hong, W, Koo, E.H
Other Authors: PHARMACOLOGY
Format: Article
Published: 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/181414
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spelling sg-nus-scholar.10635-1814142024-11-13T06:55:58Z Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP Nizetic, D Chen, C.L Hong, W Koo, E.H PHARMACOLOGY MEDICINE INSTITUTE OF MOLECULAR & CELL BIOLOGY amyloid beta protein[1-40] amyloid beta protein[1-42] amyloid precursor protein calcium channel L type cyclin dependent kinase 5 ephrin receptor B2 Fc receptor IIb gamma secretase high density lipoprotein n methyl dextro aspartic acid prion protein sorting nexin sorting nexin 27 tau protein triacylglycerol unclassified drug Alzheimer disease Article binding affinity cell activity chromosome 21 cognition cognitive defect dendritic spine Down syndrome human lipid metabolism mild cognitive impairment nerve cell nerve cell plasticity nonhuman partial trisomy pathogenesis prevalence protein expression protein function protein secretion signal transduction vascular amyloidosis vascular biology 10.3389/fnbeh.2015.00299 Frontiers in Behavioral Neuroscience 9 DEC 299 2020-10-27T10:51:04Z 2020-10-27T10:51:04Z 2015 Article Nizetic, D, Chen, C.L, Hong, W, Koo, E.H (2015). Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP. Frontiers in Behavioral Neuroscience 9 (DEC) : 299. ScholarBank@NUS Repository. https://doi.org/10.3389/fnbeh.2015.00299 16625153 https://scholarbank.nus.edu.sg/handle/10635/181414 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic amyloid beta protein[1-40]
amyloid beta protein[1-42]
amyloid precursor protein
calcium channel L type
cyclin dependent kinase 5
ephrin receptor B2
Fc receptor IIb
gamma secretase
high density lipoprotein
n methyl dextro aspartic acid
prion protein
sorting nexin
sorting nexin 27
tau protein
triacylglycerol
unclassified drug
Alzheimer disease
Article
binding affinity
cell activity
chromosome 21
cognition
cognitive defect
dendritic spine
Down syndrome
human
lipid metabolism
mild cognitive impairment
nerve cell
nerve cell plasticity
nonhuman
partial trisomy
pathogenesis
prevalence
protein expression
protein function
protein secretion
signal transduction
vascular amyloidosis
vascular biology
spellingShingle amyloid beta protein[1-40]
amyloid beta protein[1-42]
amyloid precursor protein
calcium channel L type
cyclin dependent kinase 5
ephrin receptor B2
Fc receptor IIb
gamma secretase
high density lipoprotein
n methyl dextro aspartic acid
prion protein
sorting nexin
sorting nexin 27
tau protein
triacylglycerol
unclassified drug
Alzheimer disease
Article
binding affinity
cell activity
chromosome 21
cognition
cognitive defect
dendritic spine
Down syndrome
human
lipid metabolism
mild cognitive impairment
nerve cell
nerve cell plasticity
nonhuman
partial trisomy
pathogenesis
prevalence
protein expression
protein function
protein secretion
signal transduction
vascular amyloidosis
vascular biology
Nizetic, D
Chen, C.L
Hong, W
Koo, E.H
Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP
description 10.3389/fnbeh.2015.00299
author2 PHARMACOLOGY
author_facet PHARMACOLOGY
Nizetic, D
Chen, C.L
Hong, W
Koo, E.H
format Article
author Nizetic, D
Chen, C.L
Hong, W
Koo, E.H
author_sort Nizetic, D
title Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP
title_short Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP
title_full Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP
title_fullStr Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP
title_full_unstemmed Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP
title_sort inter-dependent mechanisms behind cognitive dysfunction, vascular biology and alzheimer’s dementia in down syndrome: multi-faceted roles of app
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/181414
_version_ 1821199380421541888