Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP
10.3389/fnbeh.2015.00299
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sg-nus-scholar.10635-1814142024-11-13T06:55:58Z Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP Nizetic, D Chen, C.L Hong, W Koo, E.H PHARMACOLOGY MEDICINE INSTITUTE OF MOLECULAR & CELL BIOLOGY amyloid beta protein[1-40] amyloid beta protein[1-42] amyloid precursor protein calcium channel L type cyclin dependent kinase 5 ephrin receptor B2 Fc receptor IIb gamma secretase high density lipoprotein n methyl dextro aspartic acid prion protein sorting nexin sorting nexin 27 tau protein triacylglycerol unclassified drug Alzheimer disease Article binding affinity cell activity chromosome 21 cognition cognitive defect dendritic spine Down syndrome human lipid metabolism mild cognitive impairment nerve cell nerve cell plasticity nonhuman partial trisomy pathogenesis prevalence protein expression protein function protein secretion signal transduction vascular amyloidosis vascular biology 10.3389/fnbeh.2015.00299 Frontiers in Behavioral Neuroscience 9 DEC 299 2020-10-27T10:51:04Z 2020-10-27T10:51:04Z 2015 Article Nizetic, D, Chen, C.L, Hong, W, Koo, E.H (2015). Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP. Frontiers in Behavioral Neuroscience 9 (DEC) : 299. ScholarBank@NUS Repository. https://doi.org/10.3389/fnbeh.2015.00299 16625153 https://scholarbank.nus.edu.sg/handle/10635/181414 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031 |
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amyloid beta protein[1-40] amyloid beta protein[1-42] amyloid precursor protein calcium channel L type cyclin dependent kinase 5 ephrin receptor B2 Fc receptor IIb gamma secretase high density lipoprotein n methyl dextro aspartic acid prion protein sorting nexin sorting nexin 27 tau protein triacylglycerol unclassified drug Alzheimer disease Article binding affinity cell activity chromosome 21 cognition cognitive defect dendritic spine Down syndrome human lipid metabolism mild cognitive impairment nerve cell nerve cell plasticity nonhuman partial trisomy pathogenesis prevalence protein expression protein function protein secretion signal transduction vascular amyloidosis vascular biology |
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amyloid beta protein[1-40] amyloid beta protein[1-42] amyloid precursor protein calcium channel L type cyclin dependent kinase 5 ephrin receptor B2 Fc receptor IIb gamma secretase high density lipoprotein n methyl dextro aspartic acid prion protein sorting nexin sorting nexin 27 tau protein triacylglycerol unclassified drug Alzheimer disease Article binding affinity cell activity chromosome 21 cognition cognitive defect dendritic spine Down syndrome human lipid metabolism mild cognitive impairment nerve cell nerve cell plasticity nonhuman partial trisomy pathogenesis prevalence protein expression protein function protein secretion signal transduction vascular amyloidosis vascular biology Nizetic, D Chen, C.L Hong, W Koo, E.H Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP |
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10.3389/fnbeh.2015.00299 |
author2 |
PHARMACOLOGY |
author_facet |
PHARMACOLOGY Nizetic, D Chen, C.L Hong, W Koo, E.H |
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Article |
author |
Nizetic, D Chen, C.L Hong, W Koo, E.H |
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Nizetic, D |
title |
Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP |
title_short |
Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP |
title_full |
Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP |
title_fullStr |
Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP |
title_full_unstemmed |
Inter-dependent mechanisms behind cognitive dysfunction, vascular biology and Alzheimer’s dementia in down syndrome: Multi-faceted roles of APP |
title_sort |
inter-dependent mechanisms behind cognitive dysfunction, vascular biology and alzheimer’s dementia in down syndrome: multi-faceted roles of app |
publishDate |
2020 |
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https://scholarbank.nus.edu.sg/handle/10635/181414 |
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1821199380421541888 |