Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
10.1186/ar4140
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sg-nus-scholar.10635-1815812024-04-11T05:57:36Z Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis Aida-Yasuoka, K Peoples, C Yasuoka, H Hershberger, P Thiel, K Cauley, J.A Medsger, T.A Feghali-Bostwick, C.A OBSTETRICS & GYNAECOLOGY 1,3,5 tris(4 hydroxyphenyl) 4 propylpyrazole 1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene 2 morpholino 8 phenylchromone 4 (4 fluorophenyl) 2 (4 hydroxyphenyl) 5 (4 pyridyl)imidazole estradiol estrogen estrogen receptor alpha estrogen receptor beta estrone fibronectin fulvestrant genistein inositol 1,4,5 triphosphate inhibitor inositol 1,4,5 trisphosphate derivative mitogen activated protein kinase p38 inhibitor unclassified drug estradiol estrogen receptor antagonist fibronectin adult aged article blood sampling clinical article controlled study drug effect drug mechanism estrogen blood level estrone blood level ex vivo study human human cell human tissue in vitro study mass spectrometry mediator organ culture phenotype protein expression serum signal transduction skin skin fibroblast skin fibrosis systemic sclerosis biosynthesis blood cell culture drug effects female fibroblast fibrosis immunohistochemistry liquid chromatography metabolism middle aged pathology physiology reverse transcription polymerase chain reaction systemic sclerosis tandem mass spectrometry Western blotting Aged Blotting, Western Cells, Cultured Chromatography, Liquid Estradiol Estrogen Receptor Antagonists Female Fibroblasts Fibronectins Fibrosis Humans Immunohistochemistry Middle Aged Phenotype Reverse Transcriptase Polymerase Chain Reaction Scleroderma, Systemic Signal Transduction Tandem Mass Spectrometry 10.1186/ar4140 Arthritis Research and Therapy 15 1 R10 2020-10-27T11:22:43Z 2020-10-27T11:22:43Z 2013 Article Aida-Yasuoka, K, Peoples, C, Yasuoka, H, Hershberger, P, Thiel, K, Cauley, J.A, Medsger, T.A, Feghali-Bostwick, C.A (2013). Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis. Arthritis Research and Therapy 15 (1) : R10. ScholarBank@NUS Repository. https://doi.org/10.1186/ar4140 14786354 https://scholarbank.nus.edu.sg/handle/10635/181581 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031 |
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1,3,5 tris(4 hydroxyphenyl) 4 propylpyrazole 1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene 2 morpholino 8 phenylchromone 4 (4 fluorophenyl) 2 (4 hydroxyphenyl) 5 (4 pyridyl)imidazole estradiol estrogen estrogen receptor alpha estrogen receptor beta estrone fibronectin fulvestrant genistein inositol 1,4,5 triphosphate inhibitor inositol 1,4,5 trisphosphate derivative mitogen activated protein kinase p38 inhibitor unclassified drug estradiol estrogen receptor antagonist fibronectin adult aged article blood sampling clinical article controlled study drug effect drug mechanism estrogen blood level estrone blood level ex vivo study human human cell human tissue in vitro study mass spectrometry mediator organ culture phenotype protein expression serum signal transduction skin skin fibroblast skin fibrosis systemic sclerosis biosynthesis blood cell culture drug effects female fibroblast fibrosis immunohistochemistry liquid chromatography metabolism middle aged pathology physiology reverse transcription polymerase chain reaction systemic sclerosis tandem mass spectrometry Western blotting Aged Blotting, Western Cells, Cultured Chromatography, Liquid Estradiol Estrogen Receptor Antagonists Female Fibroblasts Fibronectins Fibrosis Humans Immunohistochemistry Middle Aged Phenotype Reverse Transcriptase Polymerase Chain Reaction Scleroderma, Systemic Signal Transduction Tandem Mass Spectrometry |
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1,3,5 tris(4 hydroxyphenyl) 4 propylpyrazole 1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene 2 morpholino 8 phenylchromone 4 (4 fluorophenyl) 2 (4 hydroxyphenyl) 5 (4 pyridyl)imidazole estradiol estrogen estrogen receptor alpha estrogen receptor beta estrone fibronectin fulvestrant genistein inositol 1,4,5 triphosphate inhibitor inositol 1,4,5 trisphosphate derivative mitogen activated protein kinase p38 inhibitor unclassified drug estradiol estrogen receptor antagonist fibronectin adult aged article blood sampling clinical article controlled study drug effect drug mechanism estrogen blood level estrone blood level ex vivo study human human cell human tissue in vitro study mass spectrometry mediator organ culture phenotype protein expression serum signal transduction skin skin fibroblast skin fibrosis systemic sclerosis biosynthesis blood cell culture drug effects female fibroblast fibrosis immunohistochemistry liquid chromatography metabolism middle aged pathology physiology reverse transcription polymerase chain reaction systemic sclerosis tandem mass spectrometry Western blotting Aged Blotting, Western Cells, Cultured Chromatography, Liquid Estradiol Estrogen Receptor Antagonists Female Fibroblasts Fibronectins Fibrosis Humans Immunohistochemistry Middle Aged Phenotype Reverse Transcriptase Polymerase Chain Reaction Scleroderma, Systemic Signal Transduction Tandem Mass Spectrometry Aida-Yasuoka, K Peoples, C Yasuoka, H Hershberger, P Thiel, K Cauley, J.A Medsger, T.A Feghali-Bostwick, C.A Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis |
description |
10.1186/ar4140 |
author2 |
OBSTETRICS & GYNAECOLOGY |
author_facet |
OBSTETRICS & GYNAECOLOGY Aida-Yasuoka, K Peoples, C Yasuoka, H Hershberger, P Thiel, K Cauley, J.A Medsger, T.A Feghali-Bostwick, C.A |
format |
Article |
author |
Aida-Yasuoka, K Peoples, C Yasuoka, H Hershberger, P Thiel, K Cauley, J.A Medsger, T.A Feghali-Bostwick, C.A |
author_sort |
Aida-Yasuoka, K |
title |
Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis |
title_short |
Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis |
title_full |
Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis |
title_fullStr |
Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis |
title_full_unstemmed |
Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis |
title_sort |
estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/181581 |
_version_ |
1800914643980386304 |