Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis

10.1186/ar4140

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Main Authors: Aida-Yasuoka, K, Peoples, C, Yasuoka, H, Hershberger, P, Thiel, K, Cauley, J.A, Medsger, T.A, Feghali-Bostwick, C.A
Other Authors: OBSTETRICS & GYNAECOLOGY
Format: Article
Published: 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/181581
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spelling sg-nus-scholar.10635-1815812024-04-11T05:57:36Z Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis Aida-Yasuoka, K Peoples, C Yasuoka, H Hershberger, P Thiel, K Cauley, J.A Medsger, T.A Feghali-Bostwick, C.A OBSTETRICS & GYNAECOLOGY 1,3,5 tris(4 hydroxyphenyl) 4 propylpyrazole 1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene 2 morpholino 8 phenylchromone 4 (4 fluorophenyl) 2 (4 hydroxyphenyl) 5 (4 pyridyl)imidazole estradiol estrogen estrogen receptor alpha estrogen receptor beta estrone fibronectin fulvestrant genistein inositol 1,4,5 triphosphate inhibitor inositol 1,4,5 trisphosphate derivative mitogen activated protein kinase p38 inhibitor unclassified drug estradiol estrogen receptor antagonist fibronectin adult aged article blood sampling clinical article controlled study drug effect drug mechanism estrogen blood level estrone blood level ex vivo study human human cell human tissue in vitro study mass spectrometry mediator organ culture phenotype protein expression serum signal transduction skin skin fibroblast skin fibrosis systemic sclerosis biosynthesis blood cell culture drug effects female fibroblast fibrosis immunohistochemistry liquid chromatography metabolism middle aged pathology physiology reverse transcription polymerase chain reaction systemic sclerosis tandem mass spectrometry Western blotting Aged Blotting, Western Cells, Cultured Chromatography, Liquid Estradiol Estrogen Receptor Antagonists Female Fibroblasts Fibronectins Fibrosis Humans Immunohistochemistry Middle Aged Phenotype Reverse Transcriptase Polymerase Chain Reaction Scleroderma, Systemic Signal Transduction Tandem Mass Spectrometry 10.1186/ar4140 Arthritis Research and Therapy 15 1 R10 2020-10-27T11:22:43Z 2020-10-27T11:22:43Z 2013 Article Aida-Yasuoka, K, Peoples, C, Yasuoka, H, Hershberger, P, Thiel, K, Cauley, J.A, Medsger, T.A, Feghali-Bostwick, C.A (2013). Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis. Arthritis Research and Therapy 15 (1) : R10. ScholarBank@NUS Repository. https://doi.org/10.1186/ar4140 14786354 https://scholarbank.nus.edu.sg/handle/10635/181581 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic 1,3,5 tris(4 hydroxyphenyl) 4 propylpyrazole
1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene
2 morpholino 8 phenylchromone
4 (4 fluorophenyl) 2 (4 hydroxyphenyl) 5 (4 pyridyl)imidazole
estradiol
estrogen
estrogen receptor alpha
estrogen receptor beta
estrone
fibronectin
fulvestrant
genistein
inositol 1,4,5 triphosphate inhibitor
inositol 1,4,5 trisphosphate derivative
mitogen activated protein kinase p38 inhibitor
unclassified drug
estradiol
estrogen receptor antagonist
fibronectin
adult
aged
article
blood sampling
clinical article
controlled study
drug effect
drug mechanism
estrogen blood level
estrone blood level
ex vivo study
human
human cell
human tissue
in vitro study
mass spectrometry
mediator
organ culture
phenotype
protein expression
serum
signal transduction
skin
skin fibroblast
skin fibrosis
systemic sclerosis
biosynthesis
blood
cell culture
drug effects
female
fibroblast
fibrosis
immunohistochemistry
liquid chromatography
metabolism
middle aged
pathology
physiology
reverse transcription polymerase chain reaction
systemic sclerosis
tandem mass spectrometry
Western blotting
Aged
Blotting, Western
Cells, Cultured
Chromatography, Liquid
Estradiol
Estrogen Receptor Antagonists
Female
Fibroblasts
Fibronectins
Fibrosis
Humans
Immunohistochemistry
Middle Aged
Phenotype
Reverse Transcriptase Polymerase Chain Reaction
Scleroderma, Systemic
Signal Transduction
Tandem Mass Spectrometry
spellingShingle 1,3,5 tris(4 hydroxyphenyl) 4 propylpyrazole
1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene
2 morpholino 8 phenylchromone
4 (4 fluorophenyl) 2 (4 hydroxyphenyl) 5 (4 pyridyl)imidazole
estradiol
estrogen
estrogen receptor alpha
estrogen receptor beta
estrone
fibronectin
fulvestrant
genistein
inositol 1,4,5 triphosphate inhibitor
inositol 1,4,5 trisphosphate derivative
mitogen activated protein kinase p38 inhibitor
unclassified drug
estradiol
estrogen receptor antagonist
fibronectin
adult
aged
article
blood sampling
clinical article
controlled study
drug effect
drug mechanism
estrogen blood level
estrone blood level
ex vivo study
human
human cell
human tissue
in vitro study
mass spectrometry
mediator
organ culture
phenotype
protein expression
serum
signal transduction
skin
skin fibroblast
skin fibrosis
systemic sclerosis
biosynthesis
blood
cell culture
drug effects
female
fibroblast
fibrosis
immunohistochemistry
liquid chromatography
metabolism
middle aged
pathology
physiology
reverse transcription polymerase chain reaction
systemic sclerosis
tandem mass spectrometry
Western blotting
Aged
Blotting, Western
Cells, Cultured
Chromatography, Liquid
Estradiol
Estrogen Receptor Antagonists
Female
Fibroblasts
Fibronectins
Fibrosis
Humans
Immunohistochemistry
Middle Aged
Phenotype
Reverse Transcriptase Polymerase Chain Reaction
Scleroderma, Systemic
Signal Transduction
Tandem Mass Spectrometry
Aida-Yasuoka, K
Peoples, C
Yasuoka, H
Hershberger, P
Thiel, K
Cauley, J.A
Medsger, T.A
Feghali-Bostwick, C.A
Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
description 10.1186/ar4140
author2 OBSTETRICS & GYNAECOLOGY
author_facet OBSTETRICS & GYNAECOLOGY
Aida-Yasuoka, K
Peoples, C
Yasuoka, H
Hershberger, P
Thiel, K
Cauley, J.A
Medsger, T.A
Feghali-Bostwick, C.A
format Article
author Aida-Yasuoka, K
Peoples, C
Yasuoka, H
Hershberger, P
Thiel, K
Cauley, J.A
Medsger, T.A
Feghali-Bostwick, C.A
author_sort Aida-Yasuoka, K
title Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
title_short Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
title_full Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
title_fullStr Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
title_full_unstemmed Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
title_sort estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/181581
_version_ 1800914643980386304