Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds

• Main Authors: Liu, Y, Krishnan, M.N, Phua, K.K.L
• Other Authors: CHEMICAL & BIOMOLECULAR ENGINEERING
• Format: Article
• Published: MDPI 2020
• Subjects: amlodipine besylate; andrographolide; beta interferon; bufalin; cardiac glycoside; digoxin; dimethyl sulfoxide; fluphenazine; gitoxin; green fluorescent protein; interleukin 1beta converting enzyme; messenger RNA; nanoparticle; ouabain; parthenolide; proscillaridin; roseolic acid; sertraline; small molecule transport agent; tetrandrine; trifluoperazine; interferon; Article; cell viability; controlled study; cytotoxicity; enzyme linked immunosorbent assay; fibroblast culture; flow cytometry; fluorescence; gene expression regulation; gene targeting; genetic transfection; human; human cell; immune response; protein expression; spectrophotometry; toxicology; transcription initiation; transcription regulation; antagonists and inhibitors; cell culture; cell survival; cytology; drug effects; fibroblast; genetic transcription; genetics; metabolism; molecular library; pharmacology; preclinical study; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Drug Evaluation, Preclinical; Fibroblasts; Green Fluorescent Proteins; Humans; Interferons; Nanoparticles; RNA, Messenger; Small Molecule Libraries; Transcription, Genetic; Transfection
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/183511
• Institution: National University of Singapore

10.3390/biom7030056