Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds

10.3390/biom7030056

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Main Authors:	Liu, Y, Krishnan, M.N, Phua, K.K.L
Other Authors:	CHEMICAL & BIOMOLECULAR ENGINEERING
Format:	Article
Published:	MDPI 2020
Subjects:	amlodipine besylate andrographolide beta interferon bufalin cardiac glycoside digoxin dimethyl sulfoxide fluphenazine gitoxin green fluorescent protein interleukin 1beta converting enzyme messenger RNA nanoparticle ouabain parthenolide proscillaridin roseolic acid sertraline small molecule transport agent tetrandrine trifluoperazine interferon Article cell viability controlled study cytotoxicity enzyme linked immunosorbent assay fibroblast culture flow cytometry fluorescence gene expression regulation gene targeting genetic transfection human human cell immune response protein expression spectrophotometry toxicology transcription initiation transcription regulation antagonists and inhibitors cell culture cell survival cytology drug effects fibroblast genetic transcription genetics metabolism molecular library pharmacology preclinical study Cell Survival Cells, Cultured Dimethyl Sulfoxide Drug Evaluation, Preclinical Fibroblasts Green Fluorescent Proteins Humans Interferons Nanoparticles RNA, Messenger Small Molecule Libraries Transcription, Genetic Transfection
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/183511
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-183511
record_format	dspace
spelling	sg-nus-scholar.10635-1835112024-03-26T08:55:16Z Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds Liu, Y Krishnan, M.N Phua, K.K.L CHEMICAL & BIOMOLECULAR ENGINEERING DUKE-NUS MEDICAL SCHOOL amlodipine besylate andrographolide beta interferon bufalin cardiac glycoside digoxin dimethyl sulfoxide fluphenazine gitoxin green fluorescent protein interleukin 1beta converting enzyme messenger RNA nanoparticle ouabain parthenolide proscillaridin roseolic acid sertraline small molecule transport agent tetrandrine trifluoperazine dimethyl sulfoxide interferon messenger RNA nanoparticle Article cell viability controlled study cytotoxicity enzyme linked immunosorbent assay fibroblast culture flow cytometry fluorescence gene expression regulation gene targeting genetic transfection human human cell immune response protein expression spectrophotometry toxicology transcription initiation transcription regulation antagonists and inhibitors cell culture cell survival cytology drug effects fibroblast genetic transcription genetics metabolism molecular library pharmacology preclinical study Cell Survival Cells, Cultured Dimethyl Sulfoxide Drug Evaluation, Preclinical Fibroblasts Green Fluorescent Proteins Humans Interferons Nanoparticles RNA, Messenger Small Molecule Libraries Transcription, Genetic Transfection 10.3390/biom7030056 Biomolecules 7 3 56 2020-11-17T04:40:05Z 2020-11-17T04:40:05Z 2017 Article Liu, Y, Krishnan, M.N, Phua, K.K.L (2017). Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds. Biomolecules 7 (3) : 56. ScholarBank@NUS Repository. https://doi.org/10.3390/biom7030056 2218-273X https://scholarbank.nus.edu.sg/handle/10635/183511 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ MDPI Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	amlodipine besylate andrographolide beta interferon bufalin cardiac glycoside digoxin dimethyl sulfoxide fluphenazine gitoxin green fluorescent protein interleukin 1beta converting enzyme messenger RNA nanoparticle ouabain parthenolide proscillaridin roseolic acid sertraline small molecule transport agent tetrandrine trifluoperazine dimethyl sulfoxide interferon messenger RNA nanoparticle Article cell viability controlled study cytotoxicity enzyme linked immunosorbent assay fibroblast culture flow cytometry fluorescence gene expression regulation gene targeting genetic transfection human human cell immune response protein expression spectrophotometry toxicology transcription initiation transcription regulation antagonists and inhibitors cell culture cell survival cytology drug effects fibroblast genetic transcription genetics metabolism molecular library pharmacology preclinical study Cell Survival Cells, Cultured Dimethyl Sulfoxide Drug Evaluation, Preclinical Fibroblasts Green Fluorescent Proteins Humans Interferons Nanoparticles RNA, Messenger Small Molecule Libraries Transcription, Genetic Transfection
spellingShingle	amlodipine besylate andrographolide beta interferon bufalin cardiac glycoside digoxin dimethyl sulfoxide fluphenazine gitoxin green fluorescent protein interleukin 1beta converting enzyme messenger RNA nanoparticle ouabain parthenolide proscillaridin roseolic acid sertraline small molecule transport agent tetrandrine trifluoperazine dimethyl sulfoxide interferon messenger RNA nanoparticle Article cell viability controlled study cytotoxicity enzyme linked immunosorbent assay fibroblast culture flow cytometry fluorescence gene expression regulation gene targeting genetic transfection human human cell immune response protein expression spectrophotometry toxicology transcription initiation transcription regulation antagonists and inhibitors cell culture cell survival cytology drug effects fibroblast genetic transcription genetics metabolism molecular library pharmacology preclinical study Cell Survival Cells, Cultured Dimethyl Sulfoxide Drug Evaluation, Preclinical Fibroblasts Green Fluorescent Proteins Humans Interferons Nanoparticles RNA, Messenger Small Molecule Libraries Transcription, Genetic Transfection Liu, Y Krishnan, M.N Phua, K.K.L Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds
description	10.3390/biom7030056
author2	CHEMICAL & BIOMOLECULAR ENGINEERING
author_facet	CHEMICAL & BIOMOLECULAR ENGINEERING Liu, Y Krishnan, M.N Phua, K.K.L
format	Article
author	Liu, Y Krishnan, M.N Phua, K.K.L
author_sort	Liu, Y
title	Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds
title_short	Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds
title_full	Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds
title_fullStr	Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds
title_full_unstemmed	Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds
title_sort	suppression of mrna nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds
publisher	MDPI
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/183511
_version_	1795301385872343040

Suppression of mRNA nanoparticle transfection in human fibroblasts by selected interferon inhibiting small molecule compounds

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