C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction

10.3390/ijms18061097

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Main Authors:	Sun, H, Zhu, X, Zhou, Y, Cai, W, Qiu, L
Other Authors:	DEPT OF PHARMACOLOGY
Format:	Article
Published:	MDPI 2020
Subjects:	complement component C1q CXCL11 chemokine endothelial nitric oxide synthase glutamate cysteine ligase heme oxygenase 1 nicotinamide adenine dinucleotide phosphate nitric oxide oxidized low density lipoprotein peroxisome proliferator activated receptor gamma coactivator 1alpha reactive oxygen metabolite small interfering RNA tumor necrosis factor adiponectin antioxidant C1QTNF9B protein, human glycoprotein hydroxymethylglutaryl coenzyme A reductase kinase low density lipoprotein PPARGC1A protein, human agar gel electrophoresis apoptosis Article cell culture cell cycle assay cell migration assay cell proliferation assay controlled study cytotoxicity endothelial dysfunction endothelium injury genetic transfection human human cell immunofluorescence test oxidative stress protein expression TUNEL assay umbilical vein endothelial cell Western blotting cell cycle cell motion cell proliferation drug effects endothelium metabolism oxidation reduction reaction pathophysiology Adiponectin AMP-Activated Protein Kinases Antioxidants Apoptosis Cell Cycle Cell Movement Cell Proliferation Endothelium Glycoproteins Human Umbilical Vein Endothelial Cells Humans Lipoproteins, LDL Nitric Oxide Nitric Oxide Synthase Type III Oxidation-Reduction Oxidative Stress Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Reactive Oxygen Species
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/183522
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1835222023-10-31T22:07:38Z C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction Sun, H Zhu, X Zhou, Y Cai, W Qiu, L DEPT OF PHARMACOLOGY complement component C1q CXCL11 chemokine endothelial nitric oxide synthase glutamate cysteine ligase heme oxygenase 1 nicotinamide adenine dinucleotide phosphate nitric oxide oxidized low density lipoprotein peroxisome proliferator activated receptor gamma coactivator 1alpha reactive oxygen metabolite small interfering RNA tumor necrosis factor adiponectin antioxidant C1QTNF9B protein, human endothelial nitric oxide synthase glycoprotein hydroxymethylglutaryl coenzyme A reductase kinase low density lipoprotein peroxisome proliferator activated receptor gamma coactivator 1alpha PPARGC1A protein, human reactive oxygen metabolite agar gel electrophoresis apoptosis Article cell culture cell cycle assay cell migration assay cell proliferation assay controlled study cytotoxicity endothelial dysfunction endothelium injury genetic transfection human human cell immunofluorescence test oxidative stress protein expression TUNEL assay umbilical vein endothelial cell Western blotting cell cycle cell motion cell proliferation drug effects endothelium metabolism oxidation reduction reaction oxidative stress pathophysiology Adiponectin AMP-Activated Protein Kinases Antioxidants Apoptosis Cell Cycle Cell Movement Cell Proliferation Endothelium Glycoproteins Human Umbilical Vein Endothelial Cells Humans Lipoproteins, LDL Nitric Oxide Nitric Oxide Synthase Type III Oxidation-Reduction Oxidative Stress Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Reactive Oxygen Species 10.3390/ijms18061097 International Journal of Molecular Sciences 18 6 1097 2020-11-17T04:42:00Z 2020-11-17T04:42:00Z 2017 Article Sun, H, Zhu, X, Zhou, Y, Cai, W, Qiu, L (2017). C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction. International Journal of Molecular Sciences 18 (6) : 1097. ScholarBank@NUS Repository. https://doi.org/10.3390/ijms18061097 1661-6596 https://scholarbank.nus.edu.sg/handle/10635/183522 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ MDPI Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	complement component C1q CXCL11 chemokine endothelial nitric oxide synthase glutamate cysteine ligase heme oxygenase 1 nicotinamide adenine dinucleotide phosphate nitric oxide oxidized low density lipoprotein peroxisome proliferator activated receptor gamma coactivator 1alpha reactive oxygen metabolite small interfering RNA tumor necrosis factor adiponectin antioxidant C1QTNF9B protein, human endothelial nitric oxide synthase glycoprotein hydroxymethylglutaryl coenzyme A reductase kinase low density lipoprotein peroxisome proliferator activated receptor gamma coactivator 1alpha PPARGC1A protein, human reactive oxygen metabolite agar gel electrophoresis apoptosis Article cell culture cell cycle assay cell migration assay cell proliferation assay controlled study cytotoxicity endothelial dysfunction endothelium injury genetic transfection human human cell immunofluorescence test oxidative stress protein expression TUNEL assay umbilical vein endothelial cell Western blotting cell cycle cell motion cell proliferation drug effects endothelium metabolism oxidation reduction reaction oxidative stress pathophysiology Adiponectin AMP-Activated Protein Kinases Antioxidants Apoptosis Cell Cycle Cell Movement Cell Proliferation Endothelium Glycoproteins Human Umbilical Vein Endothelial Cells Humans Lipoproteins, LDL Nitric Oxide Nitric Oxide Synthase Type III Oxidation-Reduction Oxidative Stress Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Reactive Oxygen Species
spellingShingle	complement component C1q CXCL11 chemokine endothelial nitric oxide synthase glutamate cysteine ligase heme oxygenase 1 nicotinamide adenine dinucleotide phosphate nitric oxide oxidized low density lipoprotein peroxisome proliferator activated receptor gamma coactivator 1alpha reactive oxygen metabolite small interfering RNA tumor necrosis factor adiponectin antioxidant C1QTNF9B protein, human endothelial nitric oxide synthase glycoprotein hydroxymethylglutaryl coenzyme A reductase kinase low density lipoprotein peroxisome proliferator activated receptor gamma coactivator 1alpha PPARGC1A protein, human reactive oxygen metabolite agar gel electrophoresis apoptosis Article cell culture cell cycle assay cell migration assay cell proliferation assay controlled study cytotoxicity endothelial dysfunction endothelium injury genetic transfection human human cell immunofluorescence test oxidative stress protein expression TUNEL assay umbilical vein endothelial cell Western blotting cell cycle cell motion cell proliferation drug effects endothelium metabolism oxidation reduction reaction oxidative stress pathophysiology Adiponectin AMP-Activated Protein Kinases Antioxidants Apoptosis Cell Cycle Cell Movement Cell Proliferation Endothelium Glycoproteins Human Umbilical Vein Endothelial Cells Humans Lipoproteins, LDL Nitric Oxide Nitric Oxide Synthase Type III Oxidation-Reduction Oxidative Stress Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Reactive Oxygen Species Sun, H Zhu, X Zhou, Y Cai, W Qiu, L C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction
description	10.3390/ijms18061097
author2	DEPT OF PHARMACOLOGY
author_facet	DEPT OF PHARMACOLOGY Sun, H Zhu, X Zhou, Y Cai, W Qiu, L
format	Article
author	Sun, H Zhu, X Zhou, Y Cai, W Qiu, L
author_sort	Sun, H
title	C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction
title_short	C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction
title_full	C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction
title_fullStr	C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction
title_full_unstemmed	C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction
title_sort	c1q/tnf-related protein-9 ameliorates ox-ldl-induced endothelial dysfunction via pgc-1²/ampk-mediated antioxidant enzyme induction
publisher	MDPI
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/183522
_version_	1781792631118888960

C1q/TNF-related protein-9 ameliorates Ox-LDL-induced endothelial dysfunction via PGC-1²/AMPK-mediated antioxidant enzyme induction

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