Inhibition of autophagy induces retinal pigment epithelial cell damage by the lipofuscin fluorophore A2E

Inhibition of autophagy induces retinal pigment epithelial cell damage by the lipofuscin fluorophore A2E

10.1016/j.fob.2014.11.003

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Bibliographic Details
Main Authors:	Saadat, K.A.S.M, Murakami, Y, Tan, X, Nomura, Y, Yasukawa, T, Okada, E, Ikeda, Y, Yanagi, Y
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	3 methyladenine adenosine triphosphate copper zinc superoxide dismutase lipofuscin lipofuscin pigment A2E manganese superoxide dismutase messenger RNA mitochondrial transcription factor A parkin peroxisome proliferator activated receptor gamma coactivator 1alpha peroxisome proliferator activated receptor gamma coactivator 1beta reactive oxygen metabolite transcription factor Nrf1 unclassified drug Article autophagosome autophagy cell damage cell death cell survival cell vacuole cell viability controlled study cytotoxicity gene expression human human cell culture mitochondrion pigment cell real time polymerase chain reaction spheroid cell transmission electron microscopy upregulation
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/183646
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Institution:	National University of Singapore

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Summary:	10.1016/j.fob.2014.11.003