Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

10.1182/blood-2010-06-289207

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Bibliographic Details
Main Authors:	Kharazi, S, Mead, A.J, Mansour, A, Hultquist, A, Böiers, C, Luc, S, Buza-Vidas, N, Ma, Z, Ferry, H, Atkinson, D, Reckzeh, K, Masson, K, Cammenga, J, Rönnstrand, L, Arai, F, Suda, T, Nerlov, C, Sitnicka, E, Jacobsen, S.E.W
Other Authors:	MEDICINE
Format:	Article
Published:	American Society of Hematology 2020
Subjects:	ataxin 1 Flt3 ligand stem cell factor allele animal experiment animal model article cell expansion controlled study cytokine production gene dosage gene duplication gene loss gene targeting granulocyte internal tandem duplication monocyte mouse myeloproliferative disorder nonhuman phenotype priority journal wild type Alleles Animals Bone Marrow Cells Cell Proliferation Cells, Cultured fms-Like Tyrosine Kinase 3 Gene Dosage Gene Duplication Gene Knock-In Techniques Loss of Heterozygosity Male Membrane Proteins Mice Mice, Inbred C57BL Mice, Transgenic Myeloproliferative Disorders Phenotype Tandem Repeat Sequences
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/183912
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Institution:	National University of Singapore

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