Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors

Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors

10.3390/cancers12082210

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Bibliographic Details
Main Authors:	Chang, Shu-Chun, Hsu, Wayne, Su, Emily Chia-Yu, Hung, Chin-Sheng, Ding, Jeak Ling
Other Authors:	BIOLOGICAL SCIENCES
Format:	Article
Language:	English
Published:	MDPI 2021
Subjects:	Science & Technology Life Sciences & Biomedicine Oncology FBXL8 SCF E3 ubiquitin ligase CCND2 IRF5 breast cancer (BRCA) and metastasis pro-tumorigenic microenvironment BREAST-CANCER CELLS NEDD8-ACTIVATING ENZYME UBIQUITINATION CHEMOKINES INFLAMMATION RECRUITMENT PROGRESSION ACTIVATION APOPTOSIS SURVIVAL
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/193718
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Institution:	National University of Singapore
Language:	English

Description
Summary:	10.3390/cancers12082210