Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors

10.3390/cancers12082210

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Main Authors: Chang, Shu-Chun, Hsu, Wayne, Su, Emily Chia-Yu, Hung, Chin-Sheng, Ding, Jeak Ling
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Language:English
Published: MDPI 2021
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/193718
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Institution: National University of Singapore
Language: English
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spelling sg-nus-scholar.10635-1937182024-04-03T07:11:18Z Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors Chang, Shu-Chun Hsu, Wayne Su, Emily Chia-Yu Hung, Chin-Sheng Ding, Jeak Ling BIOLOGICAL SCIENCES Science & Technology Life Sciences & Biomedicine Oncology FBXL8 SCF E3 ubiquitin ligase CCND2 IRF5 breast cancer (BRCA) and metastasis pro-tumorigenic microenvironment BREAST-CANCER CELLS NEDD8-ACTIVATING ENZYME UBIQUITINATION CHEMOKINES INFLAMMATION RECRUITMENT PROGRESSION ACTIVATION APOPTOSIS SURVIVAL 10.3390/cancers12082210 CANCERS 12 8 2021-07-06T10:52:40Z 2021-07-06T10:52:40Z 2020-08-01 2021-07-06T07:38:37Z Article Chang, Shu-Chun, Hsu, Wayne, Su, Emily Chia-Yu, Hung, Chin-Sheng, Ding, Jeak Ling (2020-08-01). Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors. CANCERS 12 (8). ScholarBank@NUS Repository. https://doi.org/10.3390/cancers12082210 20726694 https://scholarbank.nus.edu.sg/handle/10635/193718 en MDPI Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Life Sciences & Biomedicine
Oncology
FBXL8 SCF E3 ubiquitin ligase
CCND2
IRF5
breast cancer (BRCA) and metastasis
pro-tumorigenic microenvironment
BREAST-CANCER CELLS
NEDD8-ACTIVATING ENZYME
UBIQUITINATION
CHEMOKINES
INFLAMMATION
RECRUITMENT
PROGRESSION
ACTIVATION
APOPTOSIS
SURVIVAL
spellingShingle Science & Technology
Life Sciences & Biomedicine
Oncology
FBXL8 SCF E3 ubiquitin ligase
CCND2
IRF5
breast cancer (BRCA) and metastasis
pro-tumorigenic microenvironment
BREAST-CANCER CELLS
NEDD8-ACTIVATING ENZYME
UBIQUITINATION
CHEMOKINES
INFLAMMATION
RECRUITMENT
PROGRESSION
ACTIVATION
APOPTOSIS
SURVIVAL
Chang, Shu-Chun
Hsu, Wayne
Su, Emily Chia-Yu
Hung, Chin-Sheng
Ding, Jeak Ling
Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
description 10.3390/cancers12082210
author2 BIOLOGICAL SCIENCES
author_facet BIOLOGICAL SCIENCES
Chang, Shu-Chun
Hsu, Wayne
Su, Emily Chia-Yu
Hung, Chin-Sheng
Ding, Jeak Ling
format Article
author Chang, Shu-Chun
Hsu, Wayne
Su, Emily Chia-Yu
Hung, Chin-Sheng
Ding, Jeak Ling
author_sort Chang, Shu-Chun
title Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
title_short Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
title_full Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
title_fullStr Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
title_full_unstemmed Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
title_sort human fbxl8 is a novel e3 ligase which promotes brca metastasis by stimulating pro-tumorigenic cytokines and inhibiting tumor suppressors
publisher MDPI
publishDate 2021
url https://scholarbank.nus.edu.sg/handle/10635/193718
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