MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling
10.3389/fimmu.2019.02020
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2021
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sg-nus-scholar.10635-1937302024-04-03T09:51:56Z MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling Yang, L Ding, JL BIOLOGICAL SCIENCES IRF1 MAPK MEK inhibitor TLR7 agonist interferon macrophage reprogramming Animals Disease Models, Animal Gene Expression Profiling Gene Expression Regulation Humans Interferon Regulatory Factor-1 Interferon Regulatory Factors Interferons MAP Kinase Kinase 1 MAP Kinase Kinase 2 Macrophages Melanoma Mice Mice, Knockout Models, Biological NF-kappa B Protein Kinase Inhibitors STAT1 Transcription Factor Signal Transduction Toll-Like Receptor 7 10.3389/fimmu.2019.02020 Frontiers in Immunology 10 AUG 2020- Switzerland 2021-07-07T00:33:44Z 2021-07-07T00:33:44Z 2019-08-27 2021-07-06T07:49:33Z Article Yang, L, Ding, JL (2019-08-27). MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling. Frontiers in Immunology 10 (AUG) : 2020-. ScholarBank@NUS Repository. https://doi.org/10.3389/fimmu.2019.02020 1664-3224 https://scholarbank.nus.edu.sg/handle/10635/193730 en hdl:10635/193730 Frontiers Media SA Elements |
| institution |
National University of Singapore |
| building |
NUS Library |
| continent |
Asia |
| country |
Singapore Singapore |
| content_provider |
NUS Library |
| collection |
ScholarBank@NUS |
| language |
English |
| topic |
IRF1 MAPK MEK inhibitor TLR7 agonist interferon macrophage reprogramming Animals Disease Models, Animal Gene Expression Profiling Gene Expression Regulation Humans Interferon Regulatory Factor-1 Interferon Regulatory Factors Interferons MAP Kinase Kinase 1 MAP Kinase Kinase 2 Macrophages Melanoma Mice Mice, Knockout Models, Biological NF-kappa B Protein Kinase Inhibitors STAT1 Transcription Factor Signal Transduction Toll-Like Receptor 7 |
| spellingShingle |
IRF1 MAPK MEK inhibitor TLR7 agonist interferon macrophage reprogramming Animals Disease Models, Animal Gene Expression Profiling Gene Expression Regulation Humans Interferon Regulatory Factor-1 Interferon Regulatory Factors Interferons MAP Kinase Kinase 1 MAP Kinase Kinase 2 Macrophages Melanoma Mice Mice, Knockout Models, Biological NF-kappa B Protein Kinase Inhibitors STAT1 Transcription Factor Signal Transduction Toll-Like Receptor 7 Yang, L Ding, JL MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling |
| description |
10.3389/fimmu.2019.02020 |
| author2 |
BIOLOGICAL SCIENCES |
| author_facet |
BIOLOGICAL SCIENCES Yang, L Ding, JL |
| format |
Article |
| author |
Yang, L Ding, JL |
| author_sort |
Yang, L |
| title |
MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling |
| title_short |
MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling |
| title_full |
MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling |
| title_fullStr |
MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling |
| title_full_unstemmed |
MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling |
| title_sort |
mek1/2 inhibitors unlock the constrained interferon response in macrophages through irf1 signaling |
| publisher |
Frontiers Media SA |
| publishDate |
2021 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/193730 |
| _version_ |
1795374658658238464 |