MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling

MEK1/2 inhibitors unlock the constrained interferon response in macrophages through IRF1 signaling

10.3389/fimmu.2019.02020

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Bibliographic Details
Main Authors:	Yang, L, Ding, JL
Other Authors:	BIOLOGICAL SCIENCES
Format:	Article
Language:	English
Published:	Frontiers Media SA 2021
Subjects:	IRF1 MAPK MEK inhibitor TLR7 agonist interferon macrophage reprogramming Animals Disease Models, Animal Gene Expression Profiling Gene Expression Regulation Humans Interferon Regulatory Factor-1 Interferon Regulatory Factors Interferons MAP Kinase Kinase 1 MAP Kinase Kinase 2 Macrophages Melanoma Mice Mice, Knockout Models, Biological NF-kappa B Protein Kinase Inhibitors STAT1 Transcription Factor Signal Transduction Toll-Like Receptor 7
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/193730
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Institution:	National University of Singapore
Language:	English

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