Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice

10.3390/cells9112474

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Main Authors: Sia, K.C., Fu, Z.Y., Calne, R.Y., Nathwani, A.C., Lee, K.O., Gan, S.U.
Other Authors: SURGERY
Format: Article
Published: NLM (Medline) 2021
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/199385
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spelling sg-nus-scholar.10635-1993852024-04-25T02:37:40Z Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice Sia, K.C. Fu, Z.Y. Calne, R.Y. Nathwani, A.C. Lee, K.O. Gan, S.U. SURGERY MEDICINE adeno-associated virus serotype 8 (AAV8) albumin enhancer (3?iALB) diabetes gene therapy glucose responsive element (GlRE) liver-specific glucose-responsive promoter long-term basal insulin expression 10.3390/cells9112474 Cells 9 11 2021-08-25T14:16:31Z 2021-08-25T14:16:31Z 2020 Article Sia, K.C., Fu, Z.Y., Calne, R.Y., Nathwani, A.C., Lee, K.O., Gan, S.U. (2020). Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice. Cells 9 (11). ScholarBank@NUS Repository. https://doi.org/10.3390/cells9112474 20734409 https://scholarbank.nus.edu.sg/handle/10635/199385 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ NLM (Medline) Scopus OA2020
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic adeno-associated virus serotype 8 (AAV8)
albumin enhancer (3?iALB)
diabetes gene therapy
glucose responsive element (GlRE)
liver-specific glucose-responsive promoter
long-term basal insulin expression
spellingShingle adeno-associated virus serotype 8 (AAV8)
albumin enhancer (3?iALB)
diabetes gene therapy
glucose responsive element (GlRE)
liver-specific glucose-responsive promoter
long-term basal insulin expression
Sia, K.C.
Fu, Z.Y.
Calne, R.Y.
Nathwani, A.C.
Lee, K.O.
Gan, S.U.
Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice
description 10.3390/cells9112474
author2 SURGERY
author_facet SURGERY
Sia, K.C.
Fu, Z.Y.
Calne, R.Y.
Nathwani, A.C.
Lee, K.O.
Gan, S.U.
format Article
author Sia, K.C.
Fu, Z.Y.
Calne, R.Y.
Nathwani, A.C.
Lee, K.O.
Gan, S.U.
author_sort Sia, K.C.
title Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice
title_short Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice
title_full Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice
title_fullStr Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice
title_full_unstemmed Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice
title_sort modification of a constitutive to glucose-responsive liver-specific promoter resulted in increased efficacy of adeno-associated virus serotype 8-insulin gene therapy of diabetic mice
publisher NLM (Medline)
publishDate 2021
url https://scholarbank.nus.edu.sg/handle/10635/199385
_version_ 1800914987219156992