Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice
10.3390/cells9112474
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sg-nus-scholar.10635-1993852024-04-25T02:37:40Z Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice Sia, K.C. Fu, Z.Y. Calne, R.Y. Nathwani, A.C. Lee, K.O. Gan, S.U. SURGERY MEDICINE adeno-associated virus serotype 8 (AAV8) albumin enhancer (3?iALB) diabetes gene therapy glucose responsive element (GlRE) liver-specific glucose-responsive promoter long-term basal insulin expression 10.3390/cells9112474 Cells 9 11 2021-08-25T14:16:31Z 2021-08-25T14:16:31Z 2020 Article Sia, K.C., Fu, Z.Y., Calne, R.Y., Nathwani, A.C., Lee, K.O., Gan, S.U. (2020). Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice. Cells 9 (11). ScholarBank@NUS Repository. https://doi.org/10.3390/cells9112474 20734409 https://scholarbank.nus.edu.sg/handle/10635/199385 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ NLM (Medline) Scopus OA2020 |
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adeno-associated virus serotype 8 (AAV8) albumin enhancer (3?iALB) diabetes gene therapy glucose responsive element (GlRE) liver-specific glucose-responsive promoter long-term basal insulin expression |
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adeno-associated virus serotype 8 (AAV8) albumin enhancer (3?iALB) diabetes gene therapy glucose responsive element (GlRE) liver-specific glucose-responsive promoter long-term basal insulin expression Sia, K.C. Fu, Z.Y. Calne, R.Y. Nathwani, A.C. Lee, K.O. Gan, S.U. Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice |
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10.3390/cells9112474 |
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SURGERY |
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SURGERY Sia, K.C. Fu, Z.Y. Calne, R.Y. Nathwani, A.C. Lee, K.O. Gan, S.U. |
format |
Article |
author |
Sia, K.C. Fu, Z.Y. Calne, R.Y. Nathwani, A.C. Lee, K.O. Gan, S.U. |
author_sort |
Sia, K.C. |
title |
Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice |
title_short |
Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice |
title_full |
Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice |
title_fullStr |
Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice |
title_full_unstemmed |
Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice |
title_sort |
modification of a constitutive to glucose-responsive liver-specific promoter resulted in increased efficacy of adeno-associated virus serotype 8-insulin gene therapy of diabetic mice |
publisher |
NLM (Medline) |
publishDate |
2021 |
url |
https://scholarbank.nus.edu.sg/handle/10635/199385 |
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1800914987219156992 |