Modification of a Constitutive to Glucose-Responsive Liver-Specific Promoter Resulted in Increased Efficacy of Adeno-Associated Virus Serotype 8-Insulin Gene Therapy of Diabetic Mice

• Main Authors: Sia, K.C., Fu, Z.Y., Calne, R.Y., Nathwani, A.C., Lee, K.O., Gan, S.U.
• Other Authors: SURGERY
• Format: Article
• Published: NLM (Medline) 2021
• Subjects: adeno-associated virus serotype 8 (AAV8); albumin enhancer (3?iALB); diabetes gene therapy; glucose responsive element (GlRE); liver-specific glucose-responsive promoter; long-term basal insulin expression
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/199385
• Institution: National University of Singapore

10.3390/cells9112474