Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

10.1038/s42003-019-0634-9

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Main Authors: Bonnemaijer, P.W.M., Leeuwen, E.M., Iglesias, A.I., Gharahkhani, P., Vitart, V., Khawaja, A.P., Simcoe, M., Höhn, R., Cree, A.J., Igo, R.P., Burdon, K.P., Craig, J.E., Hewitt, A.W., Jonas, J., Khor, C.-C., Pasutto, F., Mackey, D.A., Mitchell, P., Mishra, A., Pang, C., Pasquale, L.R., Springelkamp, H., Thorleifsson, G., Thorsteinsdottir, U., Viswanathan, A.C., Wojciechowski, R., Wong, T., Young, T.L., Zeller, T., Allingham, R., Budenz, D., Bailey, J.C., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J.L., Hark, L., Hauser, M., Kang, J.H., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S., Pericak, M., Realini, A., Rhee, D., Richards, J.R., Ritch, R., Scott, W.K., Singh, K., Sit, A., Vollrath, D., Weinreb, R., Wollstein, G., Wilmer, D.Z., Atan, D., Aslam, T., Barman, S.A., Barrett, J.H., Bishop, P., Blows, P., Bunce, C., Carare, R.O., Chakravarthy, U., Chan, M., Chua, S.Y.L., Crabb, D.P., Cumberland, P.M., Day, A., Desai, P., Dhillon, B., Dick, A.D., Egan, C., Ennis, S., Foster, P., Fruttiger, M., Gallacher, J.E.J., Garway, D.F., Gibson, J., Gore, D., Guggenheim, J.A., Hardcastle, A., Harding, S.P., Hogg, R.E., Keane, P.A., Khaw, P.T., Lascaratos, G., Macgillivray, T., Mackie, S., Martin, K., McGaughey, M., McGuinness, B., McKay, G.J., McKibbin, M., Mitry, D., Moore, T., Morgan, J.E., Muthy, Z.A., O’Sullivan, E., Owen, C.G., Patel, P., Paterson, E., Peto, T., Petzold, A., Rahi, J.S., Rudnikca, A.R., Self, J., Sivaprasad, S., Steel, D., Stratton, I., Strouthidis, N., Sudlow, C., Thomas, D., Trucco, E., Tufail, A., Vernon, S.A., Williams, C., Williams, K., Woodside, J.V., Yates, M.M., Yip, J., Zheng, Y., Gerhold-Ay, A., Nickels, S., Wilson, J.F., Hayward, C., Boutin, T.S., Polašek, O., Aung, T., Amin, N., Lotery, A.J., Wiggs, J.L., Cheng, C.-Y., Hysi, P.G., Hammond, C.J., Thiadens, A.A.H.J., MacGregor, S., Klaver, C.C.W., Duijn, C.M., International Glaucoma Genetics Consortium., NEIGHBORHOOD consortium., UK Biobank Eye and Vision Consortium.
Other Authors: OPHTHALMOLOGY
Format: Article
Published: Nature Research 2021
Online Access:https://scholarbank.nus.edu.sg/handle/10635/206265
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institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
description 10.1038/s42003-019-0634-9
author2 OPHTHALMOLOGY
author_facet OPHTHALMOLOGY
Bonnemaijer, P.W.M.
Leeuwen, E.M.
Iglesias, A.I.
Gharahkhani, P.
Vitart, V.
Khawaja, A.P.
Simcoe, M.
Höhn, R.
Cree, A.J.
Igo, R.P.
Burdon, K.P.
Craig, J.E.
Hewitt, A.W.
Jonas, J.
Khor, C.-C.
Pasutto, F.
Mackey, D.A.
Mitchell, P.
Mishra, A.
Pang, C.
Pasquale, L.R.
Springelkamp, H.
Thorleifsson, G.
Thorsteinsdottir, U.
Viswanathan, A.C.
Wojciechowski, R.
Wong, T.
Young, T.L.
Zeller, T.
Allingham, R.
Budenz, D.
Bailey, J.C.
Fingert, J.
Gaasterland, D.
Gaasterland, T.
Haines, J.L.
Hark, L.
Hauser, M.
Kang, J.H.
Kraft, P.
Lee, R.
Lichter, P.
Liu, Y.
Moroi, S.
Pericak, M.
Realini, A.
Rhee, D.
Richards, J.R.
Ritch, R.
Scott, W.K.
Singh, K.
Sit, A.
Vollrath, D.
Weinreb, R.
Wollstein, G.
Wilmer, D.Z.
Atan, D.
Aslam, T.
Barman, S.A.
Barrett, J.H.
Bishop, P.
Blows, P.
Bunce, C.
Carare, R.O.
Chakravarthy, U.
Chan, M.
Chua, S.Y.L.
Crabb, D.P.
Cumberland, P.M.
Day, A.
Desai, P.
Dhillon, B.
Dick, A.D.
Egan, C.
Ennis, S.
Foster, P.
Fruttiger, M.
Gallacher, J.E.J.
Garway, D.F.
Gibson, J.
Gore, D.
Guggenheim, J.A.
Hardcastle, A.
Harding, S.P.
Hogg, R.E.
Keane, P.A.
Khaw, P.T.
Lascaratos, G.
Macgillivray, T.
Mackie, S.
Martin, K.
McGaughey, M.
McGuinness, B.
McKay, G.J.
McKibbin, M.
Mitry, D.
Moore, T.
Morgan, J.E.
Muthy, Z.A.
O’Sullivan, E.
Owen, C.G.
Patel, P.
Paterson, E.
Peto, T.
Petzold, A.
Rahi, J.S.
Rudnikca, A.R.
Self, J.
Sivaprasad, S.
Steel, D.
Stratton, I.
Strouthidis, N.
Sudlow, C.
Thomas, D.
Trucco, E.
Tufail, A.
Vernon, S.A.
Williams, C.
Williams, K.
Woodside, J.V.
Yates, M.M.
Yip, J.
Zheng, Y.
Gerhold-Ay, A.
Nickels, S.
Wilson, J.F.
Hayward, C.
Boutin, T.S.
Polašek, O.
Aung, T.
Amin, N.
Lotery, A.J.
Wiggs, J.L.
Cheng, C.-Y.
Hysi, P.G.
Hammond, C.J.
Thiadens, A.A.H.J.
MacGregor, S.
Klaver, C.C.W.
Duijn, C.M.
International Glaucoma Genetics Consortium.
NEIGHBORHOOD consortium.
UK Biobank Eye and Vision Consortium.
format Article
author Bonnemaijer, P.W.M.
Leeuwen, E.M.
Iglesias, A.I.
Gharahkhani, P.
Vitart, V.
Khawaja, A.P.
Simcoe, M.
Höhn, R.
Cree, A.J.
Igo, R.P.
Burdon, K.P.
Craig, J.E.
Hewitt, A.W.
Jonas, J.
Khor, C.-C.
Pasutto, F.
Mackey, D.A.
Mitchell, P.
Mishra, A.
Pang, C.
Pasquale, L.R.
Springelkamp, H.
Thorleifsson, G.
Thorsteinsdottir, U.
Viswanathan, A.C.
Wojciechowski, R.
Wong, T.
Young, T.L.
Zeller, T.
Allingham, R.
Budenz, D.
Bailey, J.C.
Fingert, J.
Gaasterland, D.
Gaasterland, T.
Haines, J.L.
Hark, L.
Hauser, M.
Kang, J.H.
Kraft, P.
Lee, R.
Lichter, P.
Liu, Y.
Moroi, S.
Pericak, M.
Realini, A.
Rhee, D.
Richards, J.R.
Ritch, R.
Scott, W.K.
Singh, K.
Sit, A.
Vollrath, D.
Weinreb, R.
Wollstein, G.
Wilmer, D.Z.
Atan, D.
Aslam, T.
Barman, S.A.
Barrett, J.H.
Bishop, P.
Blows, P.
Bunce, C.
Carare, R.O.
Chakravarthy, U.
Chan, M.
Chua, S.Y.L.
Crabb, D.P.
Cumberland, P.M.
Day, A.
Desai, P.
Dhillon, B.
Dick, A.D.
Egan, C.
Ennis, S.
Foster, P.
Fruttiger, M.
Gallacher, J.E.J.
Garway, D.F.
Gibson, J.
Gore, D.
Guggenheim, J.A.
Hardcastle, A.
Harding, S.P.
Hogg, R.E.
Keane, P.A.
Khaw, P.T.
Lascaratos, G.
Macgillivray, T.
Mackie, S.
Martin, K.
McGaughey, M.
McGuinness, B.
McKay, G.J.
McKibbin, M.
Mitry, D.
Moore, T.
Morgan, J.E.
Muthy, Z.A.
O’Sullivan, E.
Owen, C.G.
Patel, P.
Paterson, E.
Peto, T.
Petzold, A.
Rahi, J.S.
Rudnikca, A.R.
Self, J.
Sivaprasad, S.
Steel, D.
Stratton, I.
Strouthidis, N.
Sudlow, C.
Thomas, D.
Trucco, E.
Tufail, A.
Vernon, S.A.
Williams, C.
Williams, K.
Woodside, J.V.
Yates, M.M.
Yip, J.
Zheng, Y.
Gerhold-Ay, A.
Nickels, S.
Wilson, J.F.
Hayward, C.
Boutin, T.S.
Polašek, O.
Aung, T.
Amin, N.
Lotery, A.J.
Wiggs, J.L.
Cheng, C.-Y.
Hysi, P.G.
Hammond, C.J.
Thiadens, A.A.H.J.
MacGregor, S.
Klaver, C.C.W.
Duijn, C.M.
International Glaucoma Genetics Consortium.
NEIGHBORHOOD consortium.
UK Biobank Eye and Vision Consortium.
spellingShingle Bonnemaijer, P.W.M.
Leeuwen, E.M.
Iglesias, A.I.
Gharahkhani, P.
Vitart, V.
Khawaja, A.P.
Simcoe, M.
Höhn, R.
Cree, A.J.
Igo, R.P.
Burdon, K.P.
Craig, J.E.
Hewitt, A.W.
Jonas, J.
Khor, C.-C.
Pasutto, F.
Mackey, D.A.
Mitchell, P.
Mishra, A.
Pang, C.
Pasquale, L.R.
Springelkamp, H.
Thorleifsson, G.
Thorsteinsdottir, U.
Viswanathan, A.C.
Wojciechowski, R.
Wong, T.
Young, T.L.
Zeller, T.
Allingham, R.
Budenz, D.
Bailey, J.C.
Fingert, J.
Gaasterland, D.
Gaasterland, T.
Haines, J.L.
Hark, L.
Hauser, M.
Kang, J.H.
Kraft, P.
Lee, R.
Lichter, P.
Liu, Y.
Moroi, S.
Pericak, M.
Realini, A.
Rhee, D.
Richards, J.R.
Ritch, R.
Scott, W.K.
Singh, K.
Sit, A.
Vollrath, D.
Weinreb, R.
Wollstein, G.
Wilmer, D.Z.
Atan, D.
Aslam, T.
Barman, S.A.
Barrett, J.H.
Bishop, P.
Blows, P.
Bunce, C.
Carare, R.O.
Chakravarthy, U.
Chan, M.
Chua, S.Y.L.
Crabb, D.P.
Cumberland, P.M.
Day, A.
Desai, P.
Dhillon, B.
Dick, A.D.
Egan, C.
Ennis, S.
Foster, P.
Fruttiger, M.
Gallacher, J.E.J.
Garway, D.F.
Gibson, J.
Gore, D.
Guggenheim, J.A.
Hardcastle, A.
Harding, S.P.
Hogg, R.E.
Keane, P.A.
Khaw, P.T.
Lascaratos, G.
Macgillivray, T.
Mackie, S.
Martin, K.
McGaughey, M.
McGuinness, B.
McKay, G.J.
McKibbin, M.
Mitry, D.
Moore, T.
Morgan, J.E.
Muthy, Z.A.
O’Sullivan, E.
Owen, C.G.
Patel, P.
Paterson, E.
Peto, T.
Petzold, A.
Rahi, J.S.
Rudnikca, A.R.
Self, J.
Sivaprasad, S.
Steel, D.
Stratton, I.
Strouthidis, N.
Sudlow, C.
Thomas, D.
Trucco, E.
Tufail, A.
Vernon, S.A.
Williams, C.
Williams, K.
Woodside, J.V.
Yates, M.M.
Yip, J.
Zheng, Y.
Gerhold-Ay, A.
Nickels, S.
Wilson, J.F.
Hayward, C.
Boutin, T.S.
Polašek, O.
Aung, T.
Amin, N.
Lotery, A.J.
Wiggs, J.L.
Cheng, C.-Y.
Hysi, P.G.
Hammond, C.J.
Thiadens, A.A.H.J.
MacGregor, S.
Klaver, C.C.W.
Duijn, C.M.
International Glaucoma Genetics Consortium.
NEIGHBORHOOD consortium.
UK Biobank Eye and Vision Consortium.
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
author_sort Bonnemaijer, P.W.M.
title Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
title_short Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
title_full Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
title_fullStr Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
title_full_unstemmed Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
title_sort multi-trait genome-wide association study identifies new loci associated with optic disc parameters
publisher Nature Research
publishDate 2021
url https://scholarbank.nus.edu.sg/handle/10635/206265
_version_ 1800915089593729024
spelling sg-nus-scholar.10635-2062652024-04-12T05:48:39Z Multi-trait genome-wide association study identifies new loci associated with optic disc parameters Bonnemaijer, P.W.M. Leeuwen, E.M. Iglesias, A.I. Gharahkhani, P. Vitart, V. Khawaja, A.P. Simcoe, M. Höhn, R. Cree, A.J. Igo, R.P. Burdon, K.P. Craig, J.E. Hewitt, A.W. Jonas, J. Khor, C.-C. Pasutto, F. Mackey, D.A. Mitchell, P. Mishra, A. Pang, C. Pasquale, L.R. Springelkamp, H. Thorleifsson, G. Thorsteinsdottir, U. Viswanathan, A.C. Wojciechowski, R. Wong, T. Young, T.L. Zeller, T. Allingham, R. Budenz, D. Bailey, J.C. Fingert, J. Gaasterland, D. Gaasterland, T. Haines, J.L. Hark, L. Hauser, M. Kang, J.H. Kraft, P. Lee, R. Lichter, P. Liu, Y. Moroi, S. Pericak, M. Realini, A. Rhee, D. Richards, J.R. Ritch, R. Scott, W.K. Singh, K. Sit, A. Vollrath, D. Weinreb, R. Wollstein, G. Wilmer, D.Z. Atan, D. Aslam, T. Barman, S.A. Barrett, J.H. Bishop, P. Blows, P. Bunce, C. Carare, R.O. Chakravarthy, U. Chan, M. Chua, S.Y.L. Crabb, D.P. Cumberland, P.M. Day, A. Desai, P. Dhillon, B. Dick, A.D. Egan, C. Ennis, S. Foster, P. Fruttiger, M. Gallacher, J.E.J. Garway, D.F. Gibson, J. Gore, D. Guggenheim, J.A. Hardcastle, A. Harding, S.P. Hogg, R.E. Keane, P.A. Khaw, P.T. Lascaratos, G. Macgillivray, T. Mackie, S. Martin, K. McGaughey, M. McGuinness, B. McKay, G.J. McKibbin, M. Mitry, D. Moore, T. Morgan, J.E. Muthy, Z.A. O’Sullivan, E. Owen, C.G. Patel, P. Paterson, E. Peto, T. Petzold, A. Rahi, J.S. Rudnikca, A.R. Self, J. Sivaprasad, S. Steel, D. Stratton, I. Strouthidis, N. Sudlow, C. Thomas, D. Trucco, E. Tufail, A. Vernon, S.A. Williams, C. Williams, K. Woodside, J.V. Yates, M.M. Yip, J. Zheng, Y. Gerhold-Ay, A. Nickels, S. Wilson, J.F. Hayward, C. Boutin, T.S. Polašek, O. Aung, T. Amin, N. Lotery, A.J. Wiggs, J.L. Cheng, C.-Y. Hysi, P.G. Hammond, C.J. Thiadens, A.A.H.J. MacGregor, S. Klaver, C.C.W. Duijn, C.M. International Glaucoma Genetics Consortium. NEIGHBORHOOD consortium. UK Biobank Eye and Vision Consortium. OPHTHALMOLOGY DUKE-NUS MEDICAL SCHOOL 10.1038/s42003-019-0634-9 Communications Biology 2 1 435 2021-11-16T03:37:04Z 2021-11-16T03:37:04Z 2019 Article Bonnemaijer, P.W.M., Leeuwen, E.M., Iglesias, A.I., Gharahkhani, P., Vitart, V., Khawaja, A.P., Simcoe, M., Höhn, R., Cree, A.J., Igo, R.P., Burdon, K.P., Craig, J.E., Hewitt, A.W., Jonas, J., Khor, C.-C., Pasutto, F., Mackey, D.A., Mitchell, P., Mishra, A., Pang, C., Pasquale, L.R., Springelkamp, H., Thorleifsson, G., Thorsteinsdottir, U., Viswanathan, A.C., Wojciechowski, R., Wong, T., Young, T.L., Zeller, T., Allingham, R., Budenz, D., Bailey, J.C., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J.L., Hark, L., Hauser, M., Kang, J.H., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S., Pericak, M., Realini, A., Rhee, D., Richards, J.R., Ritch, R., Scott, W.K., Singh, K., Sit, A., Vollrath, D., Weinreb, R., Wollstein, G., Wilmer, D.Z., Atan, D., Aslam, T., Barman, S.A., Barrett, J.H., Bishop, P., Blows, P., Bunce, C., Carare, R.O., Chakravarthy, U., Chan, M., Chua, S.Y.L., Crabb, D.P., Cumberland, P.M., Day, A., Desai, P., Dhillon, B., Dick, A.D., Egan, C., Ennis, S., Foster, P., Fruttiger, M., Gallacher, J.E.J., Garway, D.F., Gibson, J., Gore, D., Guggenheim, J.A., Hardcastle, A., Harding, S.P., Hogg, R.E., Keane, P.A., Khaw, P.T., Lascaratos, G., Macgillivray, T., Mackie, S., Martin, K., McGaughey, M., McGuinness, B., McKay, G.J., McKibbin, M., Mitry, D., Moore, T., Morgan, J.E., Muthy, Z.A., O’Sullivan, E., Owen, C.G., Patel, P., Paterson, E., Peto, T., Petzold, A., Rahi, J.S., Rudnikca, A.R., Self, J., Sivaprasad, S., Steel, D., Stratton, I., Strouthidis, N., Sudlow, C., Thomas, D., Trucco, E., Tufail, A., Vernon, S.A., Williams, C., Williams, K., Woodside, J.V., Yates, M.M., Yip, J., Zheng, Y., Gerhold-Ay, A., Nickels, S., Wilson, J.F., Hayward, C., Boutin, T.S., Polašek, O., Aung, T., Amin, N., Lotery, A.J., Wiggs, J.L., Cheng, C.-Y., Hysi, P.G., Hammond, C.J., Thiadens, A.A.H.J., MacGregor, S., Klaver, C.C.W., Duijn, C.M., International Glaucoma Genetics Consortium., NEIGHBORHOOD consortium., UK Biobank Eye and Vision Consortium. (2019). Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Communications Biology 2 (1) : 435. ScholarBank@NUS Repository. https://doi.org/10.1038/s42003-019-0634-9 2399-3642 https://scholarbank.nus.edu.sg/handle/10635/206265 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ Nature Research Scopus OA2019