Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects

10.1016/j.celrep.2019.02.008

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Main Authors:	Ooi, J., Langley, S.R., Xu, X., Utami, K.H., Sim, B., Huang, Y., Harmston, N.P., Tay, Y.L., Ziaei, A., Zeng, R., Low, D., Aminkeng, F., Sobota, R.M., Ginhoux, F., Petretto, E., Pouladi, M.A.
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	Elsevier B.V. 2021
Subjects:	CAG repeat differentiation DNA damage genome editing human stem cells Huntington disease isogenic mitochondria proteomics transcriptome
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/210802
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-210802
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spelling	sg-nus-scholar.10635-2108022024-04-04T00:51:55Z Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects Ooi, J. Langley, S.R. Xu, X. Utami, K.H. Sim, B. Huang, Y. Harmston, N.P. Tay, Y.L. Ziaei, A. Zeng, R. Low, D. Aminkeng, F. Sobota, R.M. Ginhoux, F. Petretto, E. Pouladi, M.A. PHYSIOLOGY DUKE-NUS MEDICAL SCHOOL YALE-NUS COLLEGE CAG repeat differentiation DNA damage genome editing human stem cells Huntington disease isogenic mitochondria proteomics transcriptome 10.1016/j.celrep.2019.02.008 Cell Reports 26 9 2494-25080000000 2021-12-16T07:51:02Z 2021-12-16T07:51:02Z 2019 Article Ooi, J., Langley, S.R., Xu, X., Utami, K.H., Sim, B., Huang, Y., Harmston, N.P., Tay, Y.L., Ziaei, A., Zeng, R., Low, D., Aminkeng, F., Sobota, R.M., Ginhoux, F., Petretto, E., Pouladi, M.A. (2019). Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects. Cell Reports 26 (9) : 2494-25080000000. ScholarBank@NUS Repository. https://doi.org/10.1016/j.celrep.2019.02.008 22111247 https://scholarbank.nus.edu.sg/handle/10635/210802 Attribution-NonCommercial-NoDerivatives 4.0 International https://creativecommons.org/licenses/by-nc-nd/4.0/ Elsevier B.V. Scopus OA2019
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	CAG repeat differentiation DNA damage genome editing human stem cells Huntington disease isogenic mitochondria proteomics transcriptome
spellingShingle	CAG repeat differentiation DNA damage genome editing human stem cells Huntington disease isogenic mitochondria proteomics transcriptome Ooi, J. Langley, S.R. Xu, X. Utami, K.H. Sim, B. Huang, Y. Harmston, N.P. Tay, Y.L. Ziaei, A. Zeng, R. Low, D. Aminkeng, F. Sobota, R.M. Ginhoux, F. Petretto, E. Pouladi, M.A. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
description	10.1016/j.celrep.2019.02.008
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Ooi, J. Langley, S.R. Xu, X. Utami, K.H. Sim, B. Huang, Y. Harmston, N.P. Tay, Y.L. Ziaei, A. Zeng, R. Low, D. Aminkeng, F. Sobota, R.M. Ginhoux, F. Petretto, E. Pouladi, M.A.
format	Article
author	Ooi, J. Langley, S.R. Xu, X. Utami, K.H. Sim, B. Huang, Y. Harmston, N.P. Tay, Y.L. Ziaei, A. Zeng, R. Low, D. Aminkeng, F. Sobota, R.M. Ginhoux, F. Petretto, E. Pouladi, M.A.
author_sort	Ooi, J.
title	Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
title_short	Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
title_full	Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
title_fullStr	Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
title_full_unstemmed	Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
title_sort	unbiased profiling of isogenic huntington disease hpsc-derived cns and peripheral cells reveals strong cell-type specificity of cag length effects
publisher	Elsevier B.V.
publishDate	2021
url	https://scholarbank.nus.edu.sg/handle/10635/210802
_version_	1795374828975292416

Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects

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