Inhibition of Excessive Monoamine Oxidase A/B Activity Protects Against Stress-induced Neuronal Death in Huntington Disease

بواسطة Ooi, J, Hayden, M.R, Pouladi, M.A
منشور في 2020

Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment

بواسطة Utami, K.H., Yusof, N.A.B.M., Kwa, J.E., Peteri, U.-K., Castrén, M.L., Pouladi, M.A.
منشور في 2021

Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells

بواسطة Itahana Y., Zhang J., Göke J., Vardy L.A., Han R., Iwamoto K., Cukuroglu E., Robson P., Pouladi M.A., Colman A., Itahana K.
منشور في 2020

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes

بواسطة Maillet, A, Tan, K, Chai, X, Sadananda, S.N, Mehta, A, Ooi, J, Hayden, M.R, Pouladi, M.A, Ghosh, S, Shim, W, Brunham, L.R
منشور في 2020

Novel mutation in HTRA1 in a family with diffuse white matter lesions and inflammatory features

بواسطة Ziaei, A., Xu, X., Dehghani, L., Bonnard, C., Zellner, A., Ng, A.Y.J., Tohari, S., Venkatesh, B., Haffner, C., Reversade, B., Shaygannejad, V., Pouladi, M.A.
منشور في 2021

Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease

بواسطة Garcia-Miralles, M, Hong, X, Tan, L.J, Caron, N.S, Huang, Y, To, X.V, Lin, R.Y, Franciosi, S, Papapetropoulos, S, Hayardeny, L, Hayden, M.R, Chuang, K.-H, Pouladi, M.A
منشور في 2020

A thiol probe for measuring unfolded protein load and proteostasis in cells

بواسطة Chen, M.Z, Moily, N.S, Bridgford, J.L, Wood, R.J, Radwan, M, Smith, T.A, Song, Z, Tang, B.Z, Tilley, L, Xu, X, Reid, G.E, Pouladi, M.A, Hong, Y, Hatters, D.M
منشور في 2020

Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice

بواسطة Wong B.K.Y., Ehrnhoefer D.E., Graham R.K., Martin D.D.O., Ladha S., Uribe V., Stanek L.M., Franciosi S., Qiu X., Deng Y., Kovalik V., Zhang W., Pouladi M.A., Shihabuddin L.S., Hayden M.R.
منشور في 2016

pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model

بواسطة Xu, X., Ng, B., Sim, B., Radulescu, C.I., Yusof, N.A.B.M., Goh, W.I., Lin, S., Lim, J.S.Y., Cha, Y., Kusko, R., Kay, C., Ratovitski, T., Ross, C., Hayden, M.R., Wright, G., Pouladi, M.A.
منشور في 2021

Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease

بواسطة Southwell A.L., Franciosi S., Villanueva E.B., Xie Y., Winter L.A., Veeraraghavan J., Jonason A., Felczak B., Zhang W., Kovalik V., Waltl S., Hall G., Pouladi M.A., Smith E.S., Bowers W.J., Zauderer M., Hayden M.R.
منشور في 2016

Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects

بواسطة Ooi, J., Langley, S.R., Xu, X., Utami, K.H., Sim, B., Huang, Y., Harmston, N.P., Tay, Y.L., Ziaei, A., Zeng, R., Low, D., Aminkeng, F., Sobota, R.M., Ginhoux, F., Petretto, E., Pouladi, M.A.
منشور في 2021

A homozygous loss-of-function camk2a mutation causes growth delay, frequent seizures and severe intellectual disability

بواسطة Chia, P.H, Zhong, F.L, Niwa, S, Bonnard, C, Utami, K.H, Zeng, R, Lee, H, Eskin, A, Nelson, S.F, Xie, W.H, Al-Tawalbeh, S, El-Khateeb, M, Shboul, M, Pouladi, M.A, Al-Raqad, M, Reversade, B
منشور في 2020

Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle

بواسطة Julien S.G., Kim S.-Y., Brunmeir R., Sinnakannu J.R., Ge X., Li H., Ma W., Yaligar J., Bhanu Prakash K.N., Velan S.S., R�der P.V., Zhang Q., Sim C.K., Wu J., Garcia-Miralles M., Pouladi M.A., Xie W., McFarlane C., Han W., Xu F.
منشور في 2019

Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy

بواسطة Hengel, H., Bosso-Lefèvre, C., Grady, G., Szenker-Ravi, E., Li, H., Pierce, S., Lebigot, É., Tan, T.-T., Eio, M.Y., Narayanan, G., Utami, K.H., Yau, M., Handal, N., Deigendesch, W., Keimer, R., Marzouqa, H.M., Gunay-Aygun, M., Muriello, M.J., Verhelst, H., Weckhuysen, S., Mahida, S., Naidu, S., Thomas, T.G., Lim, J.Y., Tan, E.S., Haye, D., Willemsen, M.A.A.P., Oegema, R., Mitchell, W.G., Pierson, T.M., Andrews, M.V., Willing, M.C., Rodan, L.H., Barakat, T.S., van Slegtenhorst, M., Gavrilova, R.H., Martinelli, D., Gilboa, T., Tamim, A.M., Hashem, M.O., AlSayed, M.D., Abdulrahim, M.M., Al-Owain, M., Awaji, A., Mahmoud, A.A.H., Faqeih, E.A., Asmari, A.A., Algain, S.M., Jad, L.A., Aldhalaan, H.M., Helbig, I., Koolen, D.A., Riess, A., Kraegeloh-Mann, I., Bauer, P., Gulsuner, S., Stamberger, H., Ng, A.Y.J., Tang, S., Tohari, S., Keren, B., Schultz-Rogers, L.E., Klee, E.W., Barresi, S., Tartaglia, M., Mor-Shaked, H., Maddirevula, S., Begtrup, A., Telegrafi, A., Pfundt, R., Schüle, R., Ciruna, B., Bonnard, C., Pouladi, M.A., Stewart, J.C., Claridge-Chang, A., Lefeber, D.J., Alkuraya, F.S., Mathuru, A.S., Venkatesh, B., Barycki, J.J., Simpson, M.A., Jamuar, S.S., Schöls, L., Reversade, B.
منشور في 2021