Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects

• Main Authors: Ooi, J., Langley, S.R., Xu, X., Utami, K.H., Sim, B., Huang, Y., Harmston, N.P., Tay, Y.L., Ziaei, A., Zeng, R., Low, D., Aminkeng, F., Sobota, R.M., Ginhoux, F., Petretto, E., Pouladi, M.A.
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: Elsevier B.V. 2021
• Subjects: CAG repeat; differentiation; DNA damage; genome editing; human stem cells; Huntington disease; isogenic; mitochondria; proteomics; transcriptome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/210802
• Institution: National University of Singapore

10.1016/j.celrep.2019.02.008