Recent Advances in Structure, Function, and Pharmacology of Class A Lipid GPCRs: Opportunities and Challenges for Drug Discovery

Recent Advances in Structure, Function, and Pharmacology of Class A Lipid GPCRs: Opportunities and Challenges for Drug Discovery

10.3390/ph15010012

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Bibliographic Details
Main Authors:	Krishna Deepak, RNV, Verma, Ravi Kumar, Hartono, Yossa Dwi, Yew, Wen Shan, Fan, Hao
Other Authors:	BIOCHEMISTRY
Format:	Article
Language:	English
Published:	MDPI 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Chemistry, Medicinal Pharmacology & Pharmacy lipid GPCR ligand access orthosteric and allosteric binding sites drug discovery antibody computational methods prostaglandin receptor platelet-activating factor receptor sphingosine-1-phosphate receptor lysophosphatidic acid receptor leukotriene receptor free fatty acid receptor cannabinoid receptor PROTEIN-COUPLED RECEPTOR STABILIZED ACTIVE STATE CRYO-EM STRUCTURE CRYSTAL-STRUCTURE ALLOSTERIC MODULATION LIGAND-BINDING ACTIVATION MECHANISMS INSIGHTS SITES
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/218856
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Institution:	National University of Singapore
Language:	English

Description
Summary:	10.3390/ph15010012