ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model

10.1038/srep26119

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Main Authors:	Chan, Elizabeth S, Shetty, Mahesh Shivarama, Sajikumar, Sreedharan, Chen, Christopher, Soong, Tuck Wah, Wong, Boon-Seng
Other Authors:	PHYSIOLOGY
Format:	Article
Language:	English
Published:	NATURE PUBLISHING GROUP 2022
Subjects:	Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics AMYLOID PRECURSOR PROTEIN HUMAN APOLIPOPROTEIN-E PHOSPHODIESTERASE INHIBITOR ROLIPRAM RECEPTOR SUBUNIT GLUR1 LONG-TERM POTENTIATION SYNAPTIC PLASTICITY AMPA RECEPTORS TARGETED REPLACEMENT BRAIN INSULIN WATER MAZE
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/218889
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Institution:	National University of Singapore
Language:	English

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spelling	sg-nus-scholar.10635-2188892024-04-04T04:22:46Z ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model Chan, Elizabeth S Shetty, Mahesh Shivarama Sajikumar, Sreedharan Chen, Christopher Soong, Tuck Wah Wong, Boon-Seng PHYSIOLOGY PHARMACOLOGY Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics AMYLOID PRECURSOR PROTEIN HUMAN APOLIPOPROTEIN-E PHOSPHODIESTERASE INHIBITOR ROLIPRAM RECEPTOR SUBUNIT GLUR1 LONG-TERM POTENTIATION SYNAPTIC PLASTICITY AMPA RECEPTORS TARGETED REPLACEMENT BRAIN INSULIN WATER MAZE 10.1038/srep26119 SCIENTIFIC REPORTS 6 1 2022-04-11T07:58:45Z 2022-04-11T07:58:45Z 2016-05-18 2022-04-11T04:23:29Z Article Chan, Elizabeth S, Shetty, Mahesh Shivarama, Sajikumar, Sreedharan, Chen, Christopher, Soong, Tuck Wah, Wong, Boon-Seng (2016-05-18). ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model. SCIENTIFIC REPORTS 6 (1). ScholarBank@NUS Repository. https://doi.org/10.1038/srep26119 20452322 https://scholarbank.nus.edu.sg/handle/10635/218889 en NATURE PUBLISHING GROUP Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
language	English
topic	Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics AMYLOID PRECURSOR PROTEIN HUMAN APOLIPOPROTEIN-E PHOSPHODIESTERASE INHIBITOR ROLIPRAM RECEPTOR SUBUNIT GLUR1 LONG-TERM POTENTIATION SYNAPTIC PLASTICITY AMPA RECEPTORS TARGETED REPLACEMENT BRAIN INSULIN WATER MAZE
spellingShingle	Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics AMYLOID PRECURSOR PROTEIN HUMAN APOLIPOPROTEIN-E PHOSPHODIESTERASE INHIBITOR ROLIPRAM RECEPTOR SUBUNIT GLUR1 LONG-TERM POTENTIATION SYNAPTIC PLASTICITY AMPA RECEPTORS TARGETED REPLACEMENT BRAIN INSULIN WATER MAZE Chan, Elizabeth S Shetty, Mahesh Shivarama Sajikumar, Sreedharan Chen, Christopher Soong, Tuck Wah Wong, Boon-Seng ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model
description	10.1038/srep26119
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Chan, Elizabeth S Shetty, Mahesh Shivarama Sajikumar, Sreedharan Chen, Christopher Soong, Tuck Wah Wong, Boon-Seng
format	Article
author	Chan, Elizabeth S Shetty, Mahesh Shivarama Sajikumar, Sreedharan Chen, Christopher Soong, Tuck Wah Wong, Boon-Seng
author_sort	Chan, Elizabeth S
title	ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model
title_short	ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model
title_full	ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model
title_fullStr	ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model
title_full_unstemmed	ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model
title_sort	apoe4 expression accelerates hippocampus-dependent cognitive deficits by enhancing a beta impairment of insulin signaling in an alzheimer's disease mouse model
publisher	NATURE PUBLISHING GROUP
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/218889
_version_	1800915363266822144

ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model

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