A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies

10.1177/17588359221087555

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Main Authors:	Ho, Jingshan, Heong, Valerie, Yong, Wei Peng, Soo, Ross, Chee, Cheng Ean, Wong, Andrea, Sundar, Raghav, Thian, Yee Liang, Gopinathan, Anil, Pang, Mei Yan, Koe, Priscillia, Jeraj, Santhiay Nathan, Soe, Phyu Pyar, Soe, Mu Yar, Tang, Tiffany, Ng, Matthew CH, Tai, David WM, Tan, Tira JY, Xu, Hongmei, Chang, Hua, Landesman, Yosef, Shah, Jatin, Shacham, Sharon, Lee, Soo Chin, Tan, Daniel SW, Goh, Boon Cher, Tan, David SP
Other Authors:	DIAGNOSTIC RADIOLOGY
Format:	Article
Language:	English
Published:	SAGE PUBLICATIONS LTD 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Oncology advanced malignancies Asian clinical trial phase 1 selinexor ANTITUMOR-ACTIVITY DEXAMETHASONE 1ST-IN-CLASS CONSENSUS LYMPHOMA CRITERIA
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/226297
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Institution:	National University of Singapore
Language:	English

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spelling	sg-nus-scholar.10635-2262972024-11-15T08:50:48Z A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies Ho, Jingshan Heong, Valerie Yong, Wei Peng Soo, Ross Chee, Cheng Ean Wong, Andrea Sundar, Raghav Thian, Yee Liang Gopinathan, Anil Pang, Mei Yan Koe, Priscillia Jeraj, Santhiay Nathan Soe, Phyu Pyar Soe, Mu Yar Tang, Tiffany Ng, Matthew CH Tai, David WM Tan, Tira JY Xu, Hongmei Chang, Hua Landesman, Yosef Shah, Jatin Shacham, Sharon Lee, Soo Chin Tan, Daniel SW Goh, Boon Cher Tan, David SP DIAGNOSTIC RADIOLOGY MEDICINE DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) CANCER SCIENCE INSTITUTE OF SINGAPORE DUKE-NUS MEDICAL SCHOOL Assoc Prof Shao Peng, David Tan Science & Technology Life Sciences & Biomedicine Oncology advanced malignancies Asian clinical trial phase 1 selinexor ANTITUMOR-ACTIVITY DEXAMETHASONE 1ST-IN-CLASS CONSENSUS LYMPHOMA CRITERIA 10.1177/17588359221087555 THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY 14 2022-06-02T00:35:31Z 2022-06-02T00:35:31Z 2022-03-01 2022-06-01T11:31:26Z Article Ho, Jingshan, Heong, Valerie, Yong, Wei Peng, Soo, Ross, Chee, Cheng Ean, Wong, Andrea, Sundar, Raghav, Thian, Yee Liang, Gopinathan, Anil, Pang, Mei Yan, Koe, Priscillia, Jeraj, Santhiay Nathan, Soe, Phyu Pyar, Soe, Mu Yar, Tang, Tiffany, Ng, Matthew CH, Tai, David WM, Tan, Tira JY, Xu, Hongmei, Chang, Hua, Landesman, Yosef, Shah, Jatin, Shacham, Sharon, Lee, Soo Chin, Tan, Daniel SW, Goh, Boon Cher, Tan, David SP (2022-03-01). A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies. THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY 14. ScholarBank@NUS Repository. https://doi.org/10.1177/17588359221087555 17588340 17588359 https://scholarbank.nus.edu.sg/handle/10635/226297 en SAGE PUBLICATIONS LTD Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
language	English
topic	Science & Technology Life Sciences & Biomedicine Oncology advanced malignancies Asian clinical trial phase 1 selinexor ANTITUMOR-ACTIVITY DEXAMETHASONE 1ST-IN-CLASS CONSENSUS LYMPHOMA CRITERIA
spellingShingle	Science & Technology Life Sciences & Biomedicine Oncology advanced malignancies Asian clinical trial phase 1 selinexor ANTITUMOR-ACTIVITY DEXAMETHASONE 1ST-IN-CLASS CONSENSUS LYMPHOMA CRITERIA Ho, Jingshan Heong, Valerie Yong, Wei Peng Soo, Ross Chee, Cheng Ean Wong, Andrea Sundar, Raghav Thian, Yee Liang Gopinathan, Anil Pang, Mei Yan Koe, Priscillia Jeraj, Santhiay Nathan Soe, Phyu Pyar Soe, Mu Yar Tang, Tiffany Ng, Matthew CH Tai, David WM Tan, Tira JY Xu, Hongmei Chang, Hua Landesman, Yosef Shah, Jatin Shacham, Sharon Lee, Soo Chin Tan, Daniel SW Goh, Boon Cher Tan, David SP A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies
description	10.1177/17588359221087555
author2	DIAGNOSTIC RADIOLOGY
author_facet	DIAGNOSTIC RADIOLOGY Ho, Jingshan Heong, Valerie Yong, Wei Peng Soo, Ross Chee, Cheng Ean Wong, Andrea Sundar, Raghav Thian, Yee Liang Gopinathan, Anil Pang, Mei Yan Koe, Priscillia Jeraj, Santhiay Nathan Soe, Phyu Pyar Soe, Mu Yar Tang, Tiffany Ng, Matthew CH Tai, David WM Tan, Tira JY Xu, Hongmei Chang, Hua Landesman, Yosef Shah, Jatin Shacham, Sharon Lee, Soo Chin Tan, Daniel SW Goh, Boon Cher Tan, David SP
format	Article
author	Ho, Jingshan Heong, Valerie Yong, Wei Peng Soo, Ross Chee, Cheng Ean Wong, Andrea Sundar, Raghav Thian, Yee Liang Gopinathan, Anil Pang, Mei Yan Koe, Priscillia Jeraj, Santhiay Nathan Soe, Phyu Pyar Soe, Mu Yar Tang, Tiffany Ng, Matthew CH Tai, David WM Tan, Tira JY Xu, Hongmei Chang, Hua Landesman, Yosef Shah, Jatin Shacham, Sharon Lee, Soo Chin Tan, Daniel SW Goh, Boon Cher Tan, David SP
author_sort	Ho, Jingshan
title	A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies
title_short	A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies
title_full	A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies
title_fullStr	A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies
title_full_unstemmed	A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies
title_sort	phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (sine) selinexor in asian patients with advanced or metastatic malignancies
publisher	SAGE PUBLICATIONS LTD
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/226297
_version_	1821219995855618048

A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies

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