THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors

10.3390/ijms23031207

Saved in:

Bibliographic Details
Main Authors:	Shyamsunder, Pavithra, Sridharan, Shree Pooja, Madan, Vikas, Dakle, Pushkar, Zeya, Cao, Kanojia, Deepika, Chng, Wee-Joo, Ong, S Tiong, Koeffler, H Phillip
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Language:	English
Published:	MDPI 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Physical Sciences Biochemistry & Molecular Biology Chemistry, Multidisciplinary Chemistry DNA repair BRCAness THZ531 Olaparib DEPENDENT KINASE INHIBITOR STRAND BREAK REPAIR HOMOLOGOUS RECOMBINATION GENOMIC STABILITY CDK12 INHIBITION DAMAGE RESPONSE PROTEIN-KINASE WILD-TYPE EXPRESSION RESISTANCE
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/228992
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore
Language:	English

id	sg-nus-scholar.10635-228992
record_format	dspace
spelling	sg-nus-scholar.10635-2289922023-10-31T08:47:36Z THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors Shyamsunder, Pavithra Sridharan, Shree Pooja Madan, Vikas Dakle, Pushkar Zeya, Cao Kanojia, Deepika Chng, Wee-Joo Ong, S Tiong Koeffler, H Phillip CANCER SCIENCE INSTITUTE OF SINGAPORE DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) DEAN'S OFFICE (MEDICINE) DUKE-NUS MEDICAL SCHOOL Science & Technology Life Sciences & Biomedicine Physical Sciences Biochemistry & Molecular Biology Chemistry, Multidisciplinary Chemistry DNA repair BRCAness THZ531 Olaparib DEPENDENT KINASE INHIBITOR STRAND BREAK REPAIR HOMOLOGOUS RECOMBINATION GENOMIC STABILITY CDK12 INHIBITION DAMAGE RESPONSE PROTEIN-KINASE WILD-TYPE EXPRESSION RESISTANCE 10.3390/ijms23031207 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 3 2022-07-21T04:34:11Z 2022-07-21T04:34:11Z 2022-02-01 2022-07-17T12:04:08Z Article Shyamsunder, Pavithra, Sridharan, Shree Pooja, Madan, Vikas, Dakle, Pushkar, Zeya, Cao, Kanojia, Deepika, Chng, Wee-Joo, Ong, S Tiong, Koeffler, H Phillip (2022-02-01). THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (3). ScholarBank@NUS Repository. https://doi.org/10.3390/ijms23031207 16616596 14220067 https://scholarbank.nus.edu.sg/handle/10635/228992 en MDPI Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
language	English
topic	Science & Technology Life Sciences & Biomedicine Physical Sciences Biochemistry & Molecular Biology Chemistry, Multidisciplinary Chemistry DNA repair BRCAness THZ531 Olaparib DEPENDENT KINASE INHIBITOR STRAND BREAK REPAIR HOMOLOGOUS RECOMBINATION GENOMIC STABILITY CDK12 INHIBITION DAMAGE RESPONSE PROTEIN-KINASE WILD-TYPE EXPRESSION RESISTANCE
spellingShingle	Science & Technology Life Sciences & Biomedicine Physical Sciences Biochemistry & Molecular Biology Chemistry, Multidisciplinary Chemistry DNA repair BRCAness THZ531 Olaparib DEPENDENT KINASE INHIBITOR STRAND BREAK REPAIR HOMOLOGOUS RECOMBINATION GENOMIC STABILITY CDK12 INHIBITION DAMAGE RESPONSE PROTEIN-KINASE WILD-TYPE EXPRESSION RESISTANCE Shyamsunder, Pavithra Sridharan, Shree Pooja Madan, Vikas Dakle, Pushkar Zeya, Cao Kanojia, Deepika Chng, Wee-Joo Ong, S Tiong Koeffler, H Phillip THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors
description	10.3390/ijms23031207
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Shyamsunder, Pavithra Sridharan, Shree Pooja Madan, Vikas Dakle, Pushkar Zeya, Cao Kanojia, Deepika Chng, Wee-Joo Ong, S Tiong Koeffler, H Phillip
format	Article
author	Shyamsunder, Pavithra Sridharan, Shree Pooja Madan, Vikas Dakle, Pushkar Zeya, Cao Kanojia, Deepika Chng, Wee-Joo Ong, S Tiong Koeffler, H Phillip
author_sort	Shyamsunder, Pavithra
title	THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors
title_short	THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors
title_full	THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors
title_fullStr	THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors
title_full_unstemmed	THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors
title_sort	thz531 induces a state of brcaness in multiple myeloma cells: synthetic lethality with combination treatment of thz 531 with dna repair inhibitors
publisher	MDPI
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/228992
_version_	1781793147101118464

THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors

Similar Items