Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells

Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells

10.3390/cancers13050941

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Bibliographic Details
Main Authors: Dyrstad, Sissel E., Lotsberg, Maria L., Tan, Tuan Zea, Pettersen, Ina K. N., Hjellbrekke, Silje, Tusubira, Deusdedit, Engelsen, Agnete S. T., Daubon, Thomas, Mourier, Arnaud, Thiery, Jean Paul, Dahl, Olav, Lorens, James B., Tronstad, Karl Johan, Røsland, G.V.
Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
Format: Article
Published: MDPI AG 2022
Subjects:
DCA
EGFR TKI
Glycolysis
Ionizing radiation
Mitochondria
NSCLC
PDH
PDHK
Warburg effect
Online Access:https://scholarbank.nus.edu.sg/handle/10635/233232
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Institution: National University of Singapore

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https://scholarbank.nus.edu.sg/handle/10635/233232

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