Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells

10.3390/cancers13050941

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Main Authors:	Dyrstad, Sissel E., Lotsberg, Maria L., Tan, Tuan Zea, Pettersen, Ina K. N., Hjellbrekke, Silje, Tusubira, Deusdedit, Engelsen, Agnete S. T., Daubon, Thomas, Mourier, Arnaud, Thiery, Jean Paul, Dahl, Olav, Lorens, James B., Tronstad, Karl Johan, Røsland, G.V.
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	MDPI AG 2022
Subjects:	DCA EGFR TKI Glycolysis Ionizing radiation Mitochondria NSCLC PDH PDHK Warburg effect
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/233232
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-233232
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spelling	sg-nus-scholar.10635-2332322024-04-16T03:47:48Z Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells Dyrstad, Sissel E. Lotsberg, Maria L. Tan, Tuan Zea Pettersen, Ina K. N. Hjellbrekke, Silje Tusubira, Deusdedit Engelsen, Agnete S. T. Daubon, Thomas Mourier, Arnaud Thiery, Jean Paul Dahl, Olav Lorens, James B. Tronstad, Karl Johan Røsland, G.V. CANCER SCIENCE INSTITUTE OF SINGAPORE BIOCHEMISTRY DCA EGFR TKI Glycolysis Ionizing radiation Mitochondria NSCLC PDH PDHK Warburg effect 10.3390/cancers13050941 Cancers 13 5 1-28 2022-10-13T07:54:47Z 2022-10-13T07:54:47Z 2021-02-24 Article Dyrstad, Sissel E., Lotsberg, Maria L., Tan, Tuan Zea, Pettersen, Ina K. N., Hjellbrekke, Silje, Tusubira, Deusdedit, Engelsen, Agnete S. T., Daubon, Thomas, Mourier, Arnaud, Thiery, Jean Paul, Dahl, Olav, Lorens, James B., Tronstad, Karl Johan, Røsland, G.V. (2021-02-24). Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells. Cancers 13 (5) : 1-28. ScholarBank@NUS Repository. https://doi.org/10.3390/cancers13050941 2072-6694 https://scholarbank.nus.edu.sg/handle/10635/233232 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ MDPI AG Scopus OA2021
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	DCA EGFR TKI Glycolysis Ionizing radiation Mitochondria NSCLC PDH PDHK Warburg effect
spellingShingle	DCA EGFR TKI Glycolysis Ionizing radiation Mitochondria NSCLC PDH PDHK Warburg effect Dyrstad, Sissel E. Lotsberg, Maria L. Tan, Tuan Zea Pettersen, Ina K. N. Hjellbrekke, Silje Tusubira, Deusdedit Engelsen, Agnete S. T. Daubon, Thomas Mourier, Arnaud Thiery, Jean Paul Dahl, Olav Lorens, James B. Tronstad, Karl Johan Røsland, G.V. Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells
description	10.3390/cancers13050941
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Dyrstad, Sissel E. Lotsberg, Maria L. Tan, Tuan Zea Pettersen, Ina K. N. Hjellbrekke, Silje Tusubira, Deusdedit Engelsen, Agnete S. T. Daubon, Thomas Mourier, Arnaud Thiery, Jean Paul Dahl, Olav Lorens, James B. Tronstad, Karl Johan Røsland, G.V.
format	Article
author	Dyrstad, Sissel E. Lotsberg, Maria L. Tan, Tuan Zea Pettersen, Ina K. N. Hjellbrekke, Silje Tusubira, Deusdedit Engelsen, Agnete S. T. Daubon, Thomas Mourier, Arnaud Thiery, Jean Paul Dahl, Olav Lorens, James B. Tronstad, Karl Johan Røsland, G.V.
author_sort	Dyrstad, Sissel E.
title	Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells
title_short	Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells
title_full	Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells
title_fullStr	Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells
title_full_unstemmed	Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells
title_sort	blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells
publisher	MDPI AG
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/233232
_version_	1800915662057504768

Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with egfr tki and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells

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