SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling

10.1016/j.yexcr.2018.06.029

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Main Authors:	Seah, Kwi Shan, Loh, Jian Yun, Thi, Thuy Trang Nguyena, Hwei, Ling Tan, Hutchinson, Paul E, Lim, Kim Kiat, Dymock, Brian W, Long, Yun Chau, Lee Jon Deoon,Edmund, Shen, Han-Ming, Chen, Ee Sin
Other Authors:	DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
Format:	Article
Language:	English
Published:	ELSEVIER INC 2023
Subjects:	Science & Technology Life Sciences & Biomedicine Oncology Cell Biology Doxorubicin SAHA AMPK MTOR Synthetic lethality Gastric cancer ACTIVATED PROTEIN-KINASE STRAND BREAK REPAIR SYNTHETIC LETHALITY CHROMATIN-STRUCTURE H4-K16 ACETYLATION MAMMALIAN TARGET RAPAMYCIN MTOR FISSION YEAST BRCT DOMAINS HISTONE
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/239188
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Institution:	National University of Singapore
Language:	English

id	sg-nus-scholar.10635-239188
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spelling	sg-nus-scholar.10635-2391882024-04-16T05:35:21Z SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling Seah, Kwi Shan Loh, Jian Yun Thi, Thuy Trang Nguyena Hwei, Ling Tan Hutchinson, Paul E Lim, Kim Kiat Dymock, Brian W Long, Yun Chau Lee Jon Deoon,Edmund Shen, Han-Ming Chen, Ee Sin DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) BIOCHEMISTRY PHARMACOLOGY PHARMACY PHYSIOLOGY LIFE SCIENCES INSTITUTE Science & Technology Life Sciences & Biomedicine Oncology Cell Biology Doxorubicin SAHA AMPK MTOR Synthetic lethality Gastric cancer ACTIVATED PROTEIN-KINASE STRAND BREAK REPAIR SYNTHETIC LETHALITY CHROMATIN-STRUCTURE H4-K16 ACETYLATION MAMMALIAN TARGET RAPAMYCIN MTOR FISSION YEAST BRCT DOMAINS HISTONE 10.1016/j.yexcr.2018.06.029 EXPERIMENTAL CELL RESEARCH 370 2 283-291 2023-05-04T06:01:02Z 2023-05-04T06:01:02Z 2018-09-15 2023-05-02T07:56:40Z Article Seah, Kwi Shan, Loh, Jian Yun, Thi, Thuy Trang Nguyena, Hwei, Ling Tan, Hutchinson, Paul E, Lim, Kim Kiat, Dymock, Brian W, Long, Yun Chau, Lee Jon Deoon,Edmund, Shen, Han-Ming, Chen, Ee Sin (2018-09-15). SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling. EXPERIMENTAL CELL RESEARCH 370 (2) : 283-291. ScholarBank@NUS Repository. https://doi.org/10.1016/j.yexcr.2018.06.029 0014-4827 1090-2422 https://scholarbank.nus.edu.sg/handle/10635/239188 en ELSEVIER INC Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
language	English
topic	Science & Technology Life Sciences & Biomedicine Oncology Cell Biology Doxorubicin SAHA AMPK MTOR Synthetic lethality Gastric cancer ACTIVATED PROTEIN-KINASE STRAND BREAK REPAIR SYNTHETIC LETHALITY CHROMATIN-STRUCTURE H4-K16 ACETYLATION MAMMALIAN TARGET RAPAMYCIN MTOR FISSION YEAST BRCT DOMAINS HISTONE
spellingShingle	Science & Technology Life Sciences & Biomedicine Oncology Cell Biology Doxorubicin SAHA AMPK MTOR Synthetic lethality Gastric cancer ACTIVATED PROTEIN-KINASE STRAND BREAK REPAIR SYNTHETIC LETHALITY CHROMATIN-STRUCTURE H4-K16 ACETYLATION MAMMALIAN TARGET RAPAMYCIN MTOR FISSION YEAST BRCT DOMAINS HISTONE Seah, Kwi Shan Loh, Jian Yun Thi, Thuy Trang Nguyena Hwei, Ling Tan Hutchinson, Paul E Lim, Kim Kiat Dymock, Brian W Long, Yun Chau Lee Jon Deoon,Edmund Shen, Han-Ming Chen, Ee Sin SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
description	10.1016/j.yexcr.2018.06.029
author2	DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
author_facet	DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) Seah, Kwi Shan Loh, Jian Yun Thi, Thuy Trang Nguyena Hwei, Ling Tan Hutchinson, Paul E Lim, Kim Kiat Dymock, Brian W Long, Yun Chau Lee Jon Deoon,Edmund Shen, Han-Ming Chen, Ee Sin
format	Article
author	Seah, Kwi Shan Loh, Jian Yun Thi, Thuy Trang Nguyena Hwei, Ling Tan Hutchinson, Paul E Lim, Kim Kiat Dymock, Brian W Long, Yun Chau Lee Jon Deoon,Edmund Shen, Han-Ming Chen, Ee Sin
author_sort	Seah, Kwi Shan
title	SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
title_short	SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
title_full	SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
title_fullStr	SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
title_full_unstemmed	SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
title_sort	saha and cisplatin sensitize gastric cancer cells to doxorubicin by induction of dna damage, apoptosis and perturbation of ampk-mtor signalling
publisher	ELSEVIER INC
publishDate	2023
url	https://scholarbank.nus.edu.sg/handle/10635/239188
_version_	1800915824021602304

SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling

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