SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling

• Main Authors: Seah, Kwi Shan, Loh, Jian Yun, Thi, Thuy Trang Nguyena, Hwei, Ling Tan, Hutchinson, Paul E, Lim, Kim Kiat, Dymock, Brian W, Long, Yun Chau, Lee Jon Deoon,Edmund, Shen, Han-Ming, Chen, Ee Sin
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Language: English
• Published: ELSEVIER INC 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Oncology; Cell Biology; Doxorubicin; SAHA; AMPK; MTOR; Synthetic lethality; Gastric cancer; ACTIVATED PROTEIN-KINASE; STRAND BREAK REPAIR; SYNTHETIC LETHALITY; CHROMATIN-STRUCTURE; H4-K16 ACETYLATION; MAMMALIAN TARGET; RAPAMYCIN MTOR; FISSION YEAST; BRCT DOMAINS; HISTONE
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/239188
• Institution: National University of Singapore

10.1016/j.yexcr.2018.06.029