SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling

SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling

10.1016/j.yexcr.2018.06.029

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Bibliographic Details
Main Authors: Seah, Kwi Shan, Loh, Jian Yun, Thi, Thuy Trang Nguyena, Hwei, Ling Tan, Hutchinson, Paul E, Lim, Kim Kiat, Dymock, Brian W, Long, Yun Chau, Lee Jon Deoon,Edmund, Shen, Han-Ming, Chen, Ee Sin
Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
Format: Article
Language:English
Published: ELSEVIER INC 2023
Subjects:
Science & Technology
Life Sciences & Biomedicine
Oncology
Cell Biology
Doxorubicin
SAHA
AMPK
MTOR
Synthetic lethality
Gastric cancer
ACTIVATED PROTEIN-KINASE
STRAND BREAK REPAIR
SYNTHETIC LETHALITY
CHROMATIN-STRUCTURE
H4-K16 ACETYLATION
MAMMALIAN TARGET
RAPAMYCIN MTOR
FISSION YEAST
BRCT DOMAINS
HISTONE
Online Access:https://scholarbank.nus.edu.sg/handle/10635/239188
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Institution: National University of Singapore
Language: English

Internet

https://scholarbank.nus.edu.sg/handle/10635/239188

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