Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score

• Main Authors: Lim, Ashley JW, Tyniana, C Tera, Lim, Lee Jin, Tan, Justina Wei Lynn, Koh, Ee Tzun, Chong, Samuel S, Khor, Chiea Chuen, Leong, Khai Pang G, Lee, Caroline G
• Other Authors: DEAN'S OFFICE (NGS FOR INTGR SCI & ENGG)
• Format: Article
• Language: English
• Published: BMC 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Medicine, Research & Experimental; Research & Experimental Medicine; Machine-learning; Polygenic risk score; Rheumatoid arthritis; Single nucleotide polymorphisms; WHOLE-GENOME ASSOCIATION; PATHOGENESIS; GENETICS
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/243371
• Institution: National University of Singapore

10.1186/s12967-023-03939-5