PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

10.1186/s12943-023-01827-6

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Main Authors:	Glaviano, A, Foo, ASC, Lam, HY, Yap, KCH, Jacot, W, Jones, RH, Eng, H, Nair, MG, Makvandi, P, Geoerger, B, Kulke, MH, Baird, RD, Prabhu, JS, Carbone, D, Pecoraro, C, Teh, DBL, Sethi, G, Cavalieri, V, Lin, KH, Javidi-Sharifi, NR, Toska, E, Davids, MS, Brown, JR, Diana, P, Stebbing, J, Fruman, DA, Kumar, AP
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Review
Published:	Springer Science and Business Media LLC 2023
Subjects:	AKT inhibitors ATP-competitive mTOR inhibitors Allosteric mTOR inhibitors Bi-steric mTOR inhibitors Cancer Dual PI3K/mTOR inhibitors Isoform-specific PI3K inhibitors PDK1 inhibitors PI3K/AKT/mTORC pathway Pan PI3K inhibitors Humans Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Signal Transduction TOR Serine-Threonine Kinases Neoplasms
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/245930
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-2459302024-04-04T04:24:01Z PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer Glaviano, A Foo, ASC Lam, HY Yap, KCH Jacot, W Jones, RH Eng, H Nair, MG Makvandi, P Geoerger, B Kulke, MH Baird, RD Prabhu, JS Carbone, D Pecoraro, C Teh, DBL Sethi, G Cavalieri, V Lin, KH Javidi-Sharifi, NR Toska, E Davids, MS Brown, JR Diana, P Stebbing, J Fruman, DA Kumar, AP CANCER SCIENCE INSTITUTE OF SINGAPORE MICROBIOLOGY AND IMMUNOLOGY PHARMACOLOGY PHYSIOLOGY AKT inhibitors ATP-competitive mTOR inhibitors Allosteric mTOR inhibitors Bi-steric mTOR inhibitors Cancer Dual PI3K/mTOR inhibitors Isoform-specific PI3K inhibitors PDK1 inhibitors PI3K/AKT/mTORC pathway Pan PI3K inhibitors Humans Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Signal Transduction TOR Serine-Threonine Kinases Neoplasms 10.1186/s12943-023-01827-6 Molecular Cancer 22 1 138- 2023-11-14T04:51:36Z 2023-11-14T04:51:36Z 2023-12-01 2023-11-13T05:12:18Z Review Glaviano, A, Foo, ASC, Lam, HY, Yap, KCH, Jacot, W, Jones, RH, Eng, H, Nair, MG, Makvandi, P, Geoerger, B, Kulke, MH, Baird, RD, Prabhu, JS, Carbone, D, Pecoraro, C, Teh, DBL, Sethi, G, Cavalieri, V, Lin, KH, Javidi-Sharifi, NR, Toska, E, Davids, MS, Brown, JR, Diana, P, Stebbing, J, Fruman, DA, Kumar, AP (2023-12-01). PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer. Molecular Cancer 22 (1) : 138-. ScholarBank@NUS Repository. https://doi.org/10.1186/s12943-023-01827-6 1476-4598 https://scholarbank.nus.edu.sg/handle/10635/245930 Springer Science and Business Media LLC Elements
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	AKT inhibitors ATP-competitive mTOR inhibitors Allosteric mTOR inhibitors Bi-steric mTOR inhibitors Cancer Dual PI3K/mTOR inhibitors Isoform-specific PI3K inhibitors PDK1 inhibitors PI3K/AKT/mTORC pathway Pan PI3K inhibitors Humans Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Signal Transduction TOR Serine-Threonine Kinases Neoplasms
spellingShingle	AKT inhibitors ATP-competitive mTOR inhibitors Allosteric mTOR inhibitors Bi-steric mTOR inhibitors Cancer Dual PI3K/mTOR inhibitors Isoform-specific PI3K inhibitors PDK1 inhibitors PI3K/AKT/mTORC pathway Pan PI3K inhibitors Humans Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Signal Transduction TOR Serine-Threonine Kinases Neoplasms Glaviano, A Foo, ASC Lam, HY Yap, KCH Jacot, W Jones, RH Eng, H Nair, MG Makvandi, P Geoerger, B Kulke, MH Baird, RD Prabhu, JS Carbone, D Pecoraro, C Teh, DBL Sethi, G Cavalieri, V Lin, KH Javidi-Sharifi, NR Toska, E Davids, MS Brown, JR Diana, P Stebbing, J Fruman, DA Kumar, AP PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
description	10.1186/s12943-023-01827-6
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Glaviano, A Foo, ASC Lam, HY Yap, KCH Jacot, W Jones, RH Eng, H Nair, MG Makvandi, P Geoerger, B Kulke, MH Baird, RD Prabhu, JS Carbone, D Pecoraro, C Teh, DBL Sethi, G Cavalieri, V Lin, KH Javidi-Sharifi, NR Toska, E Davids, MS Brown, JR Diana, P Stebbing, J Fruman, DA Kumar, AP
format	Review
author	Glaviano, A Foo, ASC Lam, HY Yap, KCH Jacot, W Jones, RH Eng, H Nair, MG Makvandi, P Geoerger, B Kulke, MH Baird, RD Prabhu, JS Carbone, D Pecoraro, C Teh, DBL Sethi, G Cavalieri, V Lin, KH Javidi-Sharifi, NR Toska, E Davids, MS Brown, JR Diana, P Stebbing, J Fruman, DA Kumar, AP
author_sort	Glaviano, A
title	PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
title_short	PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
title_full	PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
title_fullStr	PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
title_full_unstemmed	PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
title_sort	pi3k/akt/mtor signaling transduction pathway and targeted therapies in cancer
publisher	Springer Science and Business Media LLC
publishDate	2023
url	https://scholarbank.nus.edu.sg/handle/10635/245930
_version_	1800915980249989120

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

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