Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein

Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein

10.1093/eurheartj/ehs472

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Bibliographic Details
Main Authors: Sorrentino, Vincenzo, Fouchier, Sigrid W, Motazacker, Mohammad M, Nelson, Jessica K, Defesche, Joep C, Dallinga-Thie, Geesje M, Kastelein, John JP, Hovingh, G Kees, Zelcer, Noam
Other Authors: BIOCHEMISTRY
Format: Article
Language:English
Published: OXFORD UNIV PRESS 2024
Subjects:
LDL
LDL receptor
IDOL
E3-ubiquitin ligase
Rare coding variants
AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA
Online Access:https://scholarbank.nus.edu.sg/handle/10635/247844
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Institution: National University of Singapore
Language: English

Internet

https://scholarbank.nus.edu.sg/handle/10635/247844

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