Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities

10.1158/1078-0432.CCR-20-4607

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Main Authors: Chua, Khi Pin, Teng, Yvonne HF, Tan, Aaron C, Takano, Angela, Alvarez, Jacob JS, Nahar, Rahul, Rohatgi, Neha, Lai, Gillianne GY, Aung, Zaw Win, Yeong, Joe PS, Lim, Kiat Hon, Naeini, Marjan Mojtabavi, Kassam, Irfahan, Jain, Amit, Tan, Wan Ling, Gogna, Apoorva, Too, Chow Wei, Kanesvaran, Ravindran, Ng, Quan Sing, Ang, Mei Kim, Rajasekaran, Tanujaa, Anantham, Devanand, Phua, Ghee Chee, Tan, Bien Soo, Lee, Yin Yeng, Wang, Lanying, Teo, Audrey SM, Khng, Alexis Jiaying, Lim, Ming Jie, Suteja, Lisda, Toh, Chee Keong, Lim, Wan-Teck, Iyer, N Gopalakrishna, Tam, Wai Leong, Tan, Eng-Huat, Zhai, Weiwei, Hillmer, Axel M, Skanderup, Anders J, Tan, Daniel SW
Other Authors: SURGERY
Format: Article
Language:English
Published: AMER ASSOC CANCER RESEARCH 2024
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/248932
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spelling sg-nus-scholar.10635-2489322024-11-15T08:45:40Z Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities Chua, Khi Pin Teng, Yvonne HF Tan, Aaron C Takano, Angela Alvarez, Jacob JS Nahar, Rahul Rohatgi, Neha Lai, Gillianne GY Aung, Zaw Win Yeong, Joe PS Lim, Kiat Hon Naeini, Marjan Mojtabavi Kassam, Irfahan Jain, Amit Tan, Wan Ling Gogna, Apoorva Too, Chow Wei Kanesvaran, Ravindran Ng, Quan Sing Ang, Mei Kim Rajasekaran, Tanujaa Anantham, Devanand Phua, Ghee Chee Tan, Bien Soo Lee, Yin Yeng Wang, Lanying Teo, Audrey SM Khng, Alexis Jiaying Lim, Ming Jie Suteja, Lisda Toh, Chee Keong Lim, Wan-Teck Iyer, N Gopalakrishna Tam, Wai Leong Tan, Eng-Huat Zhai, Weiwei Hillmer, Axel M Skanderup, Anders J Tan, Daniel SW SURGERY DEPARTMENT OF COMPUTER SCIENCE DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) DUKE-NUS MEDICAL SCHOOL Assoc Prof Wan-Teck Darren Lim Science & Technology Life Sciences & Biomedicine Oncology CELL LUNG-CANCER ACQUIRED-RESISTANCE 1ST-LINE TREATMENT OPEN-LABEL CHECKPOINT INHIBITORS GEFITINIB OSIMERTINIB EVOLUTION AFATINIB 10.1158/1078-0432.CCR-20-4607 CLINICAL CANCER RESEARCH 27 21 5939-5950 2024-06-15T04:53:25Z 2024-06-15T04:53:25Z 2021-11-01 2024-06-12T14:11:04Z Article Chua, Khi Pin, Teng, Yvonne HF, Tan, Aaron C, Takano, Angela, Alvarez, Jacob JS, Nahar, Rahul, Rohatgi, Neha, Lai, Gillianne GY, Aung, Zaw Win, Yeong, Joe PS, Lim, Kiat Hon, Naeini, Marjan Mojtabavi, Kassam, Irfahan, Jain, Amit, Tan, Wan Ling, Gogna, Apoorva, Too, Chow Wei, Kanesvaran, Ravindran, Ng, Quan Sing, Ang, Mei Kim, Rajasekaran, Tanujaa, Anantham, Devanand, Phua, Ghee Chee, Tan, Bien Soo, Lee, Yin Yeng, Wang, Lanying, Teo, Audrey SM, Khng, Alexis Jiaying, Lim, Ming Jie, Suteja, Lisda, Toh, Chee Keong, Lim, Wan-Teck, Iyer, N Gopalakrishna, Tam, Wai Leong, Tan, Eng-Huat, Zhai, Weiwei, Hillmer, Axel M, Skanderup, Anders J, Tan, Daniel SW (2021-11-01). Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities. CLINICAL CANCER RESEARCH 27 (21) : 5939-5950. ScholarBank@NUS Repository. https://doi.org/10.1158/1078-0432.CCR-20-4607 1078-0432 1557-3265 https://scholarbank.nus.edu.sg/handle/10635/248932 en AMER ASSOC CANCER RESEARCH Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Life Sciences & Biomedicine
Oncology
CELL LUNG-CANCER
ACQUIRED-RESISTANCE
1ST-LINE TREATMENT
OPEN-LABEL
CHECKPOINT INHIBITORS
GEFITINIB
OSIMERTINIB
EVOLUTION
AFATINIB
spellingShingle Science & Technology
Life Sciences & Biomedicine
Oncology
CELL LUNG-CANCER
ACQUIRED-RESISTANCE
1ST-LINE TREATMENT
OPEN-LABEL
CHECKPOINT INHIBITORS
GEFITINIB
OSIMERTINIB
EVOLUTION
AFATINIB
Chua, Khi Pin
Teng, Yvonne HF
Tan, Aaron C
Takano, Angela
Alvarez, Jacob JS
Nahar, Rahul
Rohatgi, Neha
Lai, Gillianne GY
Aung, Zaw Win
Yeong, Joe PS
Lim, Kiat Hon
Naeini, Marjan Mojtabavi
Kassam, Irfahan
Jain, Amit
Tan, Wan Ling
Gogna, Apoorva
Too, Chow Wei
Kanesvaran, Ravindran
Ng, Quan Sing
Ang, Mei Kim
Rajasekaran, Tanujaa
Anantham, Devanand
Phua, Ghee Chee
Tan, Bien Soo
Lee, Yin Yeng
Wang, Lanying
Teo, Audrey SM
Khng, Alexis Jiaying
Lim, Ming Jie
Suteja, Lisda
Toh, Chee Keong
Lim, Wan-Teck
Iyer, N Gopalakrishna
Tam, Wai Leong
Tan, Eng-Huat
Zhai, Weiwei
Hillmer, Axel M
Skanderup, Anders J
Tan, Daniel SW
Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
description 10.1158/1078-0432.CCR-20-4607
author2 SURGERY
author_facet SURGERY
Chua, Khi Pin
Teng, Yvonne HF
Tan, Aaron C
Takano, Angela
Alvarez, Jacob JS
Nahar, Rahul
Rohatgi, Neha
Lai, Gillianne GY
Aung, Zaw Win
Yeong, Joe PS
Lim, Kiat Hon
Naeini, Marjan Mojtabavi
Kassam, Irfahan
Jain, Amit
Tan, Wan Ling
Gogna, Apoorva
Too, Chow Wei
Kanesvaran, Ravindran
Ng, Quan Sing
Ang, Mei Kim
Rajasekaran, Tanujaa
Anantham, Devanand
Phua, Ghee Chee
Tan, Bien Soo
Lee, Yin Yeng
Wang, Lanying
Teo, Audrey SM
Khng, Alexis Jiaying
Lim, Ming Jie
Suteja, Lisda
Toh, Chee Keong
Lim, Wan-Teck
Iyer, N Gopalakrishna
Tam, Wai Leong
Tan, Eng-Huat
Zhai, Weiwei
Hillmer, Axel M
Skanderup, Anders J
Tan, Daniel SW
format Article
author Chua, Khi Pin
Teng, Yvonne HF
Tan, Aaron C
Takano, Angela
Alvarez, Jacob JS
Nahar, Rahul
Rohatgi, Neha
Lai, Gillianne GY
Aung, Zaw Win
Yeong, Joe PS
Lim, Kiat Hon
Naeini, Marjan Mojtabavi
Kassam, Irfahan
Jain, Amit
Tan, Wan Ling
Gogna, Apoorva
Too, Chow Wei
Kanesvaran, Ravindran
Ng, Quan Sing
Ang, Mei Kim
Rajasekaran, Tanujaa
Anantham, Devanand
Phua, Ghee Chee
Tan, Bien Soo
Lee, Yin Yeng
Wang, Lanying
Teo, Audrey SM
Khng, Alexis Jiaying
Lim, Ming Jie
Suteja, Lisda
Toh, Chee Keong
Lim, Wan-Teck
Iyer, N Gopalakrishna
Tam, Wai Leong
Tan, Eng-Huat
Zhai, Weiwei
Hillmer, Axel M
Skanderup, Anders J
Tan, Daniel SW
author_sort Chua, Khi Pin
title Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
title_short Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
title_full Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
title_fullStr Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
title_full_unstemmed Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
title_sort integrative profiling of t790m-negative egfr-mutated nsclc reveals pervasive lineage transition and therapeutic opportunities
publisher AMER ASSOC CANCER RESEARCH
publishDate 2024
url https://scholarbank.nus.edu.sg/handle/10635/248932
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