B-cell Epitope Prediction through a Graph Model

• Main Authors: ZHAO, Liang, WONG, Limsoon, LU, Lanyuan, HOI, Steven C. H., LI, Jinyan
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2012
• Subjects: Protein Data Bank; Accessible Surface Area; Boundary Edge; Residue Type; Residue Pair; Bioinformatics; Computer Sciences; Databases and Information Systems
• Online Access: https://ink.library.smu.edu.sg/sis_research/2271; https://ink.library.smu.edu.sg/context/sis_research/article/3271/viewcontent/B_CellEpitopePrediction_2012.pdf
• Institution: Singapore Management University

Prediction of B-cell epitopes from antigens is useful to understand the immune basis of antibody-antigen recognition, and is helpful in vaccine design and drug development. Tremendous efforts have been devoted to this long-studied problem, however, existing methods have at least two common limitatio...