Calcium-induced Cardiac Mitochondrial Dysfunction Is Predominantly Mediated by Cyclosporine A-dependent Mitochondrial Permeability Transition Pore

Background and Aims: Cardiac mitochondrial Ca 2+ overload plays a critical role in mechanical and electrical dysfunction leading to cardiac cell death and fatal arrhythmia. Because Ca 2+ overload is related to mitochondrial permeability transition, reactive oxygen species (ROS) production and membra...

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Bibliographic Details
Main Authors: Yarana C., Sripetchwandee J., Sanit J., Chattipakorn S., Chattipakorn N.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84866143717&partnerID=40&md5=4c770efa2534432db96db5eaf7d2a985
http://cmuir.cmu.ac.th/handle/6653943832/1155
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Institution: Chiang Mai University
Language: English