Calcium-induced Cardiac Mitochondrial Dysfunction Is Predominantly Mediated by Cyclosporine A-dependent Mitochondrial Permeability Transition Pore
Background and Aims: Cardiac mitochondrial Ca 2+ overload plays a critical role in mechanical and electrical dysfunction leading to cardiac cell death and fatal arrhythmia. Because Ca 2+ overload is related to mitochondrial permeability transition, reactive oxygen species (ROS) production and membra...
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Main Authors: | Yarana C., Sripetchwandee J., Sanit J., Chattipakorn S., Chattipakorn N. |
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Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84866143717&partnerID=40&md5=4c770efa2534432db96db5eaf7d2a985 http://cmuir.cmu.ac.th/handle/6653943832/1155 |
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Institution: | Chiang Mai University |
Language: | English |
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