Mass spectrometry-based detection of hemoglobin E mutation by allele-specific base extension reaction
Background: The specific detection of a minor population of mutant DNA molecules requires methods of high specificity and sensitivity. While the single-allele base extension reaction (SABER) was shown to be useful for the detection of certain beta-thalassemia mutations, we encountered problems with...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-36649013864&partnerID=40&md5=c56e771376d52fe8ef702dcb54037ee0 http://cmuir.cmu.ac.th/handle/6653943832/2093 |
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| Institution: | Chiang Mai University |
| Language: | English |