Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance

Multidrug resistance (MDR) is a major factor in the failure of chemotherapy in cancer patients. Resistance to chemotherapy has been correlated to the overexpression of ABC drug transporters including P-glycoprotein (P-gp) that actively efflux chemotherapeutic drugs from cancer cells. Our previous st...

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Bibliographic Details
Main Authors: Pitchakarn P., Ohnuma S., Pintha K., Pompimon W., Ambudkar S.V., Limtrakul P.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-83355172162&partnerID=40&md5=ea0d81fab8097b08a618fea769370b4a
http://www.ncbi.nlm.nih.gov/pubmed/21414769
http://cmuir.cmu.ac.th/handle/6653943832/2683
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Institution: Chiang Mai University
Language: English
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