Stemona alkaloids, from traditional Thai medicine, increase chemosensitivity via P-glycoprotein-mediated multidrug resistance

P-glycoprotein-mediated drug efflux can cause a multidrug resistance (MDR) phenotype that is associated with a poor response to cancer chemotherapy. Through bioassay-guided fractionation, active Stemona alkaloids were isolated from the roots of Stemona aphylla and S. burkillii. The chemical structur...

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Bibliographic Details
Main Authors: Chanmahasathien W., Ampasavate C., Greger H., Limtrakul P.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-78651336302&partnerID=40&md5=bb972698761568a8a72c9881acfb619e
http://www.ncbi.nlm.nih.gov/pubmed/20739156
http://cmuir.cmu.ac.th/handle/6653943832/2718
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Institution: Chiang Mai University
Language: English
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