Effect of a novel oral active iron chelator: 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) in iron-overloaded and non-overloaded mice
Objective: To evaluate efficacy and toxicity of a novel orally active bidentate iron chelator, 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) in mice under normal and iron overload conditions. Methods: Wild type C57BL/6 mice were fed with normal and 0.2% (w/w) ferrocene-supplemented...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier (Singapore) Pte Ltd
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84908174801&partnerID=40&md5=e9cee701de687080bb4d9bf71ec05f1c http://cmuir.cmu.ac.th/handle/6653943832/37617 |
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| Institution: | Chiang Mai University |
| Language: | English |