A DFT study of the unusual substrate-assisted mechanism of Serratia marcescens chitinase B reveals the role of solvent and mutational effect on catalysis
© 2014 Elsevier Inc. All rights reserved. Serratia marcescens chitinase B (SmChiB) catalyzes the hydrolysis of β-1,4-glycosidic bond, via an unusual substrate-assisted mechanism, in which the substrate itself acts as an intramolecular nucleophile. In this paper, the catalytic mechanism of SmChiB has...
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Main Authors: | Jitonnom,J., Sattayanon,C., Kungwan,N., Hannongbua,S. |
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Format: | Article |
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Elsevier Inc.
2015
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Online Access: | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84919800770&origin=inward http://cmuir.cmu.ac.th/handle/6653943832/38846 |
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Institution: | Chiang Mai University |
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