Inhibition of p38 MAPK during ischemia, but not reperfusion, effectively attenuates fatal arrhythmia in ischemia/reperfusion heart

ABSTRACT:: The mitogen-activated protein kinases (MAPKs) play an important role in ischemia/reperfusion (I/R) injury. Previous evidence suggests that p38 MAPK inhibition before ischemia is cardioprotective. However, whether p38 MAPK inhibition during ischemia or reperfusion provides cardioprotection...

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Bibliographic Details
Main Authors: Surinkaew S., Kumphune S., Chattipakorn S., Chattipakorn N.
Format: Article
Language:English
Published: 2014
Online Access:http://www.ncbi.nlm.nih.gov/pubmed/23107875
http://www.scopus.com/inward/record.url?eid=2-s2.0-84873407517&partnerID=40&md5=3e12fc367ae1dcd2c6024e96a30e3675
http://cmuir.cmu.ac.th/handle/6653943832/3995
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Institution: Chiang Mai University
Language: English

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