Involvement of the P2X7 purinergic receptor and c-Jun N-terminal and extracellular signal-regulated kinases in cyclooxygenase-2 and prostaglandin E2 induction by LL-37

Involvement of the P2X7 purinergic receptor and c-Jun N-terminal and extracellular signal-regulated kinases in cyclooxygenase-2 and prostaglandin E2 induction by LL-37

Periodontal disease is caused by microorganisms and host-derived inflammation involving increased cyclooxygenase-2 (COX-2) expression and prostaglandin E2 (PGE2) production. We previously demonstrated that human β-defensin-3 induces COX-2 and PGE2 in human gingival fibroblasts (HGFs). We, therefore,...

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書目詳細資料
Main Authors:	Chotjumlong P., Bolscher J.G., Nazmi K., Reutrakul V., Supanchart C., Buranaphatthana W., Krisanaprakornkit S.
格式:	Article
語言:	English
出版:	2014
在線閱讀:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84872276132&partnerID=40&md5=ea2e6c670e2a54ef354c160f0b18cd68 http://cmuir.cmu.ac.th/handle/6653943832/4019
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