Varying Chirality Across Nicotinic Acetylcholine Receptor Subtypes: Selective Binding of Quinuclidine Triazole Compounds

© 2016 American Chemical Society. The novel quinuclidine anti-1,2,3-triazole derivatives T1-T6 were designed based on the structure of QND8. The binding studies revealed that the stereochemistry at the C3 position of the quinuclidine scaffold plays an important role in the nAChR subtype selectivity....

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Bibliographic Details
Main Authors: Sarasamkan J., Scheunemann M., Apaijai N., Palee S., Parichatikanond W., Arunrungvichian K., Fischer S., Chattipakorn S., Deuther-Conrad W., Schüürmann G., Brust P., Vajragupta O.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84991574459&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/41431
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Institution: Chiang Mai University

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