Involvement of the P2X<inf>7</inf>purinergic receptor and c-Jun N-terminal and extracellular signal-regulated kinases in cyclooxygenase-2 and prostaglandin E<inf>2</inf>induction by LL-37
Periodontal disease is caused by microorganisms and host-derived inflammation involving increased cyclooxygenase-2 (COX-2) expression and prostaglandin E 2 (PGE 2 ) production. We previously demonstrated that human β-defensin-3 induces COX-2 and PGE 2 in human gingival fibroblasts (HGFs). We, theref...
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| Main Authors: | , , , , , , |
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| Format: | Journal |
| Published: |
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84872276132&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/48338 |
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| Institution: | Chiang Mai University |