N,N,N-Trimethyl chitosan nanoparticles for the delivery of monoclonal antibodies against hepatocellular carcinoma cells

N,N,N-Trimethyl chitosan chloride is capable of forming nanocomplexes with protein through ionotropic gelation. A monoclonal antibody, raised against human liver heparan sulfate proteoglycan and specifically inhibiting hepatocellular carcinoma in vitro, was prepared in nanocomplexes of this modified...

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Main Authors: Preeyanat Vongchan, Yupanan Wutti-In, Warayuth Sajomsang, Pattarapond Gonil, Suchart Kothan, Robert J. Linhardt
格式: 雜誌
出版: 2018
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在線閱讀:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79953672031&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49838
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機構: Chiang Mai University