N,N,N-Trimethyl chitosan nanoparticles for the delivery of monoclonal antibodies against hepatocellular carcinoma cells
N,N,N-Trimethyl chitosan chloride is capable of forming nanocomplexes with protein through ionotropic gelation. A monoclonal antibody, raised against human liver heparan sulfate proteoglycan and specifically inhibiting hepatocellular carcinoma in vitro, was prepared in nanocomplexes of this modified...
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Main Authors: | Preeyanat Vongchan, Yupanan Wutti-In, Warayuth Sajomsang, Pattarapond Gonil, Suchart Kothan, Robert J. Linhardt |
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Format: | Journal |
Published: |
2018
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Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79953672031&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/49838 |
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Institution: | Chiang Mai University |
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