N,N,N-Trimethyl chitosan nanoparticles for the delivery of monoclonal antibodies against hepatocellular carcinoma cells
N,N,N-Trimethyl chitosan chloride is capable of forming nanocomplexes with protein through ionotropic gelation. A monoclonal antibody, raised against human liver heparan sulfate proteoglycan and specifically inhibiting hepatocellular carcinoma in vitro, was prepared in nanocomplexes of this modified...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-79953672031&partnerID=40&md5=d0bc3ce8d307fe8d0b581c4cd6bed471 http://www.ncbi.nlm.nih.gov/pubmed/21552341 http://cmuir.cmu.ac.th/handle/6653943832/757 |
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| Institution: | Chiang Mai University |
| Language: | English |