Identification of Pfdhfr mutant variants in plasmodium berghei model

• المؤلفون الرئيسيون: Wachiraporn Tipsuwan, Somdet Srichairatanakool, Sumalee Kamchonwongpaisan, Yongyuth Yuthavong, Chairat Uthaipibull
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Multidisciplinary
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84874528388&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/50378

Parasite resistance to antimalarials is a major burden in controlling malaria disease. Genetic mutations within the parasites are found to be the factor in conferring resistance to drugs. In this study, the power of random mutant library and transgenic parasite systems were employed to identify muta...