Improvement of the oligonucleotide ligation assay for detection of the M184V drug-resistant mutation in patients infected with human immunodeficiency virus type 1 subtype CRF01_AE

• Main Authors: Sirikwan Dokuta, Utaiwan Utaipat, Jutarat Praparattanapan, Jeitsada Keitkarn, Niwat Maneekarn, Thira Sirisanthana, Khuanchai Supparatpinyo
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876984572&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/52637
• Institution: Chiang Mai University

Methods based on genetic sequencing to monitor drug-resistance mutations in human immunodeficiency virus type 1 (HIV-1) require expensive instruments and are only capable of detecting mutant strains comprising >20% of virus populations. The National Institutes of Health's AIDS Research and R...