ClC-7 expression levels critically regulate bone turnover, but not gastric acid secretion

Mutations in the 2Cl-/1H+-exchanger ClC-7 impair osteoclast function and cause different types of osteoclast-rich osteopetrosis. However, it is unknown to what extent ClC-7 function has to be reduced to become rate-limiting for bone resorption. In osteoclasts from osteopetrosis patients expression o...

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Main Authors: C. Supanchart, L. Wartosch, C. Schlack, J. Kühnisch, D. Felsenberg, J. C. Fuhrmann, M. C. de Vernejoul, T. J. Jentsch, U. Kornak
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84886859886&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/53299
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Institution: Chiang Mai University

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