Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines

© 2016 Elsevier Ltd A convenient one-pot protocol for the synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines is reported. In the presence of the Ph3P–I2/Et3N system, a variety of secondary amides were smoothly reacted with primary or secondary amines to afford the corresponding amidi...

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Main Authors:	Wong Phakhodee, Sirilak Wangngae, Nittaya Wiriya, Mookda Pattarawarapan
Format:	Journal
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994028119&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55261
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-55261
record_format	dspace
spelling	th-cmuir.6653943832-552612018-09-05T03:12:36Z Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines Wong Phakhodee Sirilak Wangngae Nittaya Wiriya Mookda Pattarawarapan Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics © 2016 Elsevier Ltd A convenient one-pot protocol for the synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines is reported. In the presence of the Ph3P–I2/Et3N system, a variety of secondary amides were smoothly reacted with primary or secondary amines to afford the corresponding amidines in good to excellent yields under mild conditions. 2018-09-05T02:53:45Z 2018-09-05T02:53:45Z 2016-01-01 Journal 18733581 00404039 2-s2.0-84994028119 10.1016/j.tetlet.2016.10.069 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994028119&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55261
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics Wong Phakhodee Sirilak Wangngae Nittaya Wiriya Mookda Pattarawarapan Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines
description	© 2016 Elsevier Ltd A convenient one-pot protocol for the synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines is reported. In the presence of the Ph3P–I2/Et3N system, a variety of secondary amides were smoothly reacted with primary or secondary amines to afford the corresponding amidines in good to excellent yields under mild conditions.
format	Journal
author	Wong Phakhodee Sirilak Wangngae Nittaya Wiriya Mookda Pattarawarapan
author_facet	Wong Phakhodee Sirilak Wangngae Nittaya Wiriya Mookda Pattarawarapan
author_sort	Wong Phakhodee
title	Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines
title_short	Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines
title_full	Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines
title_fullStr	Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines
title_full_unstemmed	Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines
title_sort	ph<inf>3</inf>p/i<inf>2</inf>-mediated synthesis of n,n′-disubstituted and n,n,n′-trisubstituted amidines
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994028119&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55261
_version_	1681424472998936576

Ph<inf>3</inf>P/I<inf>2</inf>-mediated synthesis of N,N′-disubstituted and N,N,N′-trisubstituted amidines

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