Fibroblast growth factor-21 restores insulin sensitivity but induces aberrant bone microstructure in obese insulin-resistant rats

• Main Authors: Narattaphol Charoenphandhu, Panan Suntornsaratoon, Nateetip Krishnamra, Piangkwan Sa-nguanmoo, Pongpun Tanajak, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Nipon Chattipakorn, Siriporn Chattipakorn
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84962293972&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/56794
• Institution: Chiang Mai University

© 2016, The Japanese Society for Bone and Mineral Research and Springer Japan. Fibroblast growth factor (FGF)-21 is a potent endocrine factor that improves insulin resistance and obesity-associated metabolic disorders. However, concomitant activation of peroxisome proliferator-activated receptor-γ b...